Compare the mechanisms by which acetylation and methylation of histone lysines affect transcription. Be sure to...
Compare the mechanisms by which acetylation and methylation of histone lysines affect transcription. Be sure to discuss how these modifications impact the charge of the lysine and the association of other proteins.
Homework Answers
The acetyl groups have a negative charge on them and the methyl groups are a neutral group and somewhat positive charged. Acetylation of the histone lysine residues renders the positive charge on the lysine residue to reduce and also the subsequent methylation of the DNA renders the negative charge of the DNA to be neutral and hence due to these similar charges on both histones and DNA, the DNA becomes loose on the histone proteins and hence the DNA will be available for transcription. Hence due to acetylation and methylation, the transcription is favoured.
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Compare the mechanisms by which acetylation and methylation of
histone lysines affect transcription. Be sure to...
2. Compare the mechanisms by which acetylation and methylation of histone lysines affect transcription. Be sure...
2. Compare the mechanisms by which acetylation and methylation of histone lysines affect transcription. Be sure to discuss how these modifications impact the charge of the lysine and the association of other proteins.
Which of the following histone modifications generally PREVENTS transcription from occurring? Methylation o acetylation Demethylation Phosphorylation
Which of the following histone modifications generally PREVENTS transcription from occurring? Methylation o acetylation Demethylation Phosphorylation
Which of the following accurately matches a histone tail modification with its effect on transcription? Group...
Which of the following accurately matches a histone tail modification with its effect on transcription? Group of answer choices a Methylation of lysine 4 on the H3 tail activates transcription of downstream genes b Methylation of lysine 4 on the H3 tail activates transcription of upstream genes c Acetylation of lysine 16 on H4 prevents transcription from taking place by blocking RNA polymerase from binding d Acetylation of lysine 16 on H4 prevents transcription from taking place by preventing nucleosome...
In contrast to histone acetylation, which always correlates with gene activation, histone methylation can lead to...
In contrast to histone acetylation, which always correlates with gene activation, histone methylation can lead to either transcriptional activation or repression. How do you suppose that the same modification - methylation - can mediate different biological outcomes? Explain what is meant when we say two DNA sequences are 'highly conserved'. Why are some sequences conserved and others aren't? In your own words, explain what is meant by "position effect". What is the molecular basis of this phenomenon?
Which statements about the modification of chromatin structure in eukaryotes are true? 2 pts a. Acetylation...
Which statements about the modification of chromatin structure in eukaryotes are true? 2 pts a. Acetylation of histone tails in chromatin allows access to DNA for transcription. b. Histone proteins are always permanently placed along a DNA sequence but the binding to DNA can be loosened. c. Methylation of DNA is associated with the gene activation. d. Acetylation of histone tails is a reversible process. e. Some forms of chromatin modification can be passed on to future generations of cells.
molecular biology 16. Histone acetyltransferases would be directly involved in which of the following? A. Formation of open chromatin B. Movement of the nucleosome C. Acetylation of lysines D. Termin...
molecular biology
16. Histone acetyltransferases would be directly involved in which of the following? A. Formation of open chromatin B. Movement of the nucleosome C. Acetylation of lysines D. Termination of gene expression E. All of the above are true. 17. What functions are accomplished by the primosome? A. Tracking along DNA B. Tracking along DNA, separating double-stranded DNA C. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers D. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers, adding...
Part 1. Eukaryotes use at least two distinct mechanisms to control gene expression by altering the...
Part 1. Eukaryotes use at least two distinct mechanisms to control gene expression by altering the structure of chromatin around a particular gene. One of these mechanisms is the covalent modification of histones to switch DNA between an open and closed confirmation. A second mechanism is the covalent modification of DNA (typically on cytosines) by methylation. A. Describe a type of histone modification and explain what effect is has on chromatin, and how that effect is achieved. a. One type...
The observation that in any DNA sample, A T and G C A. DNase sequencing An...
The observation that in any DNA sample, A T and G C A. DNase sequencing An analytical method that determines which segments of DNA are bound by a particular B. Chargaff's rule protein factor, such as a transcription factor C. ChIP sequencing D. Euchromatin E. Histone acetylation F. major groove - # Areas associated with a eukaryotic gene that are where most DNA methylation occurs. # An analytical technique that involves a small slide or chip with many segments of...
4) What happens when the ribosomal complex encounters a stop codon? Explain which, if any, tRNAs...
4) What happens when the ribosomal complex encounters a stop codon? Explain which, if any, tRNAs or proteins are involved 5)If the following DNA strand was used as a template, what would the sequence of an RNA be? 5́ GTACCGTC 3́ 6) How does acetylation of the chromatin affect the translation of genes contained within? In other words, does acetylation allow or inhibit transcription, and how?
21: Met c aion of the Polamino 21. Which of the following would NOT Change the...
21: Met c aion of the Polamino 21. Which of the following would NOT Change the structure and function of a protein A Methylation of a protein B. Lipid modification of a protein C. Change in the length of the Poly A tail of the mRNA transcript encoding a protein D. Change in the position of reactive amino acids E. Proteolysis 22. Two peptides have almost the exact same primary structure, except that one has about 10 fewer amino acids...
2. Compare the mechanisms by which acetylation and methylation of histone lysines affect transcription. Be sure to discuss how these modifications impact the charge of the lysine and the association of other proteins.
Which of the following histone modifications generally PREVENTS transcription from occurring? Methylation o acetylation Demethylation Phosphorylation
In contrast to histone acetylation, which always correlates with gene activation, histone methylation can lead to either transcriptional activation or repression. How do you suppose that the same modification - methylation - can mediate different biological outcomes? Explain what is meant when we say two DNA sequences are 'highly conserved'. Why are some sequences conserved and others aren't? In your own words, explain what is meant by "position effect". What is the molecular basis of this phenomenon?
molecular biology
16. Histone acetyltransferases would be directly involved in which of the following? A. Formation of open chromatin B. Movement of the nucleosome C. Acetylation of lysines D. Termination of gene expression E. All of the above are true. 17. What functions are accomplished by the primosome? A. Tracking along DNA B. Tracking along DNA, separating double-stranded DNA C. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers D. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers, adding...
Part 1. Eukaryotes use at least two distinct mechanisms to control gene expression by altering the structure of chromatin around a particular gene. One of these mechanisms is the covalent modification of histones to switch DNA between an open and closed confirmation. A second mechanism is the covalent modification of DNA (typically on cytosines) by methylation. A. Describe a type of histone modification and explain what effect is has on chromatin, and how that effect is achieved. a. One type...
The observation that in any DNA sample, A T and G C A. DNase sequencing An analytical method that determines which segments of DNA are bound by a particular B. Chargaff's rule protein factor, such as a transcription factor C. ChIP sequencing D. Euchromatin E. Histone acetylation F. major groove - # Areas associated with a eukaryotic gene that are where most DNA methylation occurs. # An analytical technique that involves a small slide or chip with many segments of...
21: Met c aion of the Polamino 21. Which of the following would NOT Change the structure and function of a protein A Methylation of a protein B. Lipid modification of a protein C. Change in the length of the Poly A tail of the mRNA transcript encoding a protein D. Change in the position of reactive amino acids E. Proteolysis 22. Two peptides have almost the exact same primary structure, except that one has about 10 fewer amino acids...
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