2. Compare the mechanisms by which acetylation and methylation of histone lysines affect transcription. Be sure...
Compare the mechanisms by which acetylation and methylation of histone lysines affect transcription. Be sure to discuss how these modifications impact the charge of the lysine and the association of other proteins.
Which of the following histone modifications generally PREVENTS transcription from occurring? Methylation o acetylation Demethylation Phosphorylation
Which of the following accurately matches a histone tail modification with its effect on transcription? Group of answer choices a Methylation of lysine 4 on the H3 tail activates transcription of downstream genes b Methylation of lysine 4 on the H3 tail activates transcription of upstream genes c Acetylation of lysine 16 on H4 prevents transcription from taking place by blocking RNA polymerase from binding d Acetylation of lysine 16 on H4 prevents transcription from taking place by preventing nucleosome...
In contrast to histone acetylation, which always correlates with gene activation, histone methylation can lead to either transcriptional activation or repression. How do you suppose that the same modification - methylation - can mediate different biological outcomes? Explain what is meant when we say two DNA sequences are 'highly conserved'. Why are some sequences conserved and others aren't? In your own words, explain what is meant by "position effect". What is the molecular basis of this phenomenon?
Which statements about the modification of chromatin structure in eukaryotes are true? 2 pts a. Acetylation of histone tails in chromatin allows access to DNA for transcription. b. Histone proteins are always permanently placed along a DNA sequence but the binding to DNA can be loosened. c. Methylation of DNA is associated with the gene activation. d. Acetylation of histone tails is a reversible process. e. Some forms of chromatin modification can be passed on to future generations of cells.
molecular biology
16. Histone acetyltransferases would be directly involved in which of the following? A. Formation of open chromatin B. Movement of the nucleosome C. Acetylation of lysines D. Termination of gene expression E. All of the above are true. 17. What functions are accomplished by the primosome? A. Tracking along DNA B. Tracking along DNA, separating double-stranded DNA C. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers D. Tracking along DNA, separating double-stranded DNA, synthesizing RNA primers, adding...
The observation that in any DNA sample, A T and G C A. DNase sequencing An analytical method that determines which segments of DNA are bound by a particular B. Chargaff's rule protein factor, such as a transcription factor C. ChIP sequencing D. Euchromatin E. Histone acetylation F. major groove - # Areas associated with a eukaryotic gene that are where most DNA methylation occurs. # An analytical technique that involves a small slide or chip with many segments of...
RESPIRATION 2 1. Which are the factors that affect diffusion of gases across the alveolar membrane? 2. Describe different respiratory units in terms of ventilation/perfusion ratio. 3. How are Oxygen and CO2 transported in blood? 4. What is physiological dead space? Know the formula for calculation alveolar ventilation rate. 5. Describe location of chemoreceptors. Which stimuli affect their activity? 6. Describe all lung receptors. What are the effects of sympathetic and parasympathetic nervous system on respiration? OBSTRUCTIVE & RESTRICTIVE DISEASES...
t. Provide TWO (2) arguments as to why this antibacterial should only be available with a doctor's prescription. (5 marks) Question 4 Recommended time - 20 min Addiction to drugs con coeur due to psychological and/or physical dependence. a Discuss the factors that underlie physical and psychological dependence, explaining the role each plays in addiction. (8 min) b. Compare and contrast the addictive potential of cocaine, LSD and morphine, using your response to (1) and the mechanisms of action of...
2. a) It is 1 July 2022. Martins plc has gone through a period of retrenchment which has meant that for the last six years dividends have been held constant at 5p per share per annum. A dividend of 5p per share has been paid on the 30 June 2022. The market expects the annual dividends to remain at this level for the next three years (the next dividend is due in one year's time) and then to increase at...