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Question 6
6. (10 pts) For the following step in the citric acid cycle, COO H...
6. (10 pts) For the following step in the citric acid cycle, COO H COO CH...
6. (10 pts) For the following step in the citric acid cycle, COO H COO CH Succinate dehydrogenase + FAD + FADH CH, OOC H COO Succinate Fumarate a. What class of enzyme catalyzes this reaction? b. How does this step ultimately contribute to the formation of ATP? Be specific, c. Knowing that the next step is a hydration of the alkene, briefly explain why this step needed to occur? That is, why not hydrate the succinate?
1. The enzyme responsible for the substrate level phosphorylation in the citric acid cycle is: a...
1. The enzyme responsible for the substrate level phosphorylation in the citric acid cycle is: a succinate dehydrogenase b. a-ketoglutarate dehydrogenase c. succinyl thiokinase d. isocitrate dehydrogenase e. aconitase 2. Which of the listed enzymes of the TCA cycle does not represent a regulatory enzyme?: a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. a-ketoglutarate dehydrogenase complex e. citrate synthase 3. Oxidative decarboxylation of pyruvic acid is regulated by: a. cyclic AMP-dependent mechanism b. cyclic AMP-independent mechanism 4. The...
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column...
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hint(s) Reset Help isocitrate dehydrogenase aconitase citrate synthase fumarate hydratase succinate dehydrogenase succinyl-CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase In step 1, oxaloacetate condenses with acetyl-CoA to form citrate, which is catalyzed by...
need help with the blank please Certain microorganisms with an incomplete citric acid cycle decarboxylate a-ketoglutarate...
need help with the blank please
Certain microorganisms with an incomplete citric acid cycle decarboxylate a-ketoglutarate to produce succinate semialdehyde. A dehydrogenase then converts succinate semialdehyde to succinate. Соо Coo CH, CH, NAD NADH CH, CH CH Co COO 000 -ketoglutarate Succinate Succinate semialdehyde These reactions can be combined with other standard citric acid cycle reactions to create a pathway from citrate to oxaloacetate that bypasses the reaction catalyzed by Dehydrogenase Tha reaction, a step that is accompanied by the...
Incorrect Question 3 0/1 pts Which enzyme is the link between the citric acid cycle and...
Incorrect Question 3 0/1 pts Which enzyme is the link between the citric acid cycle and ATP formation? succinatethiokinase succinate dehydrogenase malate dehydrogenase citrate synthase isocitrate dehydrogenase
Acetyl COA + H2O Coo- o coo- Citrate synthase CH2 -OH -ooc— CH2 CH2 NADH +...
Acetyl COA + H2O Coo- o coo- Citrate synthase CH2 -OH -ooc— CH2 CH2 NADH + H+ COO- Oxaloacetate Coo- Citrate Aconitase Malate dehydrogenase NAD+ - Çoo- Çoo- ---OH -O00—-H HO-CH CH2 CH2 Coo- Malate Coo- Isocitrate Isocitrate lyase Malate synthase COO- COO- Coh CH2 Acetyl COA + H2O Ho Glyoxylate coo Succinate Figure 17.23 Biochemistry, Seventh Edition 2012 W. H. Freeman and Company Question 1 (10 pts) Using diagrams show the pathway that is used to convert succinate to...
Electron transport chain. The enzyme succinate dehydrogenase is part of the citric acid cycle (Fig. 17.15)...
Electron transport chain. The enzyme succinate dehydrogenase is part of the citric acid cycle (Fig. 17.15) and the electron transport chain (Fig. 18.6). Calculate the free energy (ΔG) of the reaction catalyzed by succinate dehydrogenase under physiological conditions: 2 mM succinate, 0.5 mM fumarate, 2 mM FAD, and 0.2 mM FADH2. [Recall that ΔG = -n F ΔEo. See Table 18.1 for the relevant standard reduction potential (ΔEo).]
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled...
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled in the diagram, reactions 1, 3, and 4 are regulation points in the citric acid cycle. oxaloacetate citrate synthase citrate NADH +Hi 7 malate dehydrogenase NAD malate aconitase 2 Which molecule inhibits reaction 1? isocitrate 7 fumarase NAD isocitrate dehydrogenase 3 NADH + H+ O citrate O NAD acetyl-CoA + CO2 fumarate C-ketoglutarate FADH succinate O dehydrogenase FAD O-ketoglutarate a dehydrogenase NAD + COA...
One of the early steps in the citric acid cycle is the conversion of oxaloacetate to...
One of the early steps in the
citric acid cycle is the conversion of oxaloacetate to citrate..
see picture for more details
1. One of the early steps in the citric acid cycle is the conversion of oxaloacetate to citrate (see below). Propose a mechanism for this two step process using water and acidic/basic groups on the enzyme as needed (think NAC and NAS) OOC COO S- CoA. CH H20 O -C HO O -C CH citrate synthase CH CH2...
PLEASE ANSWER ALL PARTS. THANK YOU! 10. (12 pts) During cellular respiration the energy from oxidizing...
PLEASE ANSWER ALL PARTS. THANK YOU!
10. (12 pts) During cellular respiration the energy from oxidizing glucose to CO2 is used to synthesize ATP. NADH is an important intermediate that feeds electrons into the electron chain. A. (6 pts) Write down the net chemical equations (reactants products) that generate NADH in the citric acid cycle. Make sure to also name the enzymes that catalyze each individual reaction. B. (2 pts) All the dehydrogenases of glycolysis and the citric acid cycle...
6. (10 pts) For the following step in the citric acid cycle, COO H COO CH Succinate dehydrogenase + FAD + FADH CH, OOC H COO Succinate Fumarate a. What class of enzyme catalyzes this reaction? b. How does this step ultimately contribute to the formation of ATP? Be specific, c. Knowing that the next step is a hydration of the alkene, briefly explain why this step needed to occur? That is, why not hydrate the succinate?
1. The enzyme responsible for the substrate level phosphorylation in the citric acid cycle is: a succinate dehydrogenase b. a-ketoglutarate dehydrogenase c. succinyl thiokinase d. isocitrate dehydrogenase e. aconitase 2. Which of the listed enzymes of the TCA cycle does not represent a regulatory enzyme?: a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. a-ketoglutarate dehydrogenase complex e. citrate synthase 3. Oxidative decarboxylation of pyruvic acid is regulated by: a. cyclic AMP-dependent mechanism b. cyclic AMP-independent mechanism 4. The...
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hint(s) Reset Help isocitrate dehydrogenase aconitase citrate synthase fumarate hydratase succinate dehydrogenase succinyl-CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase In step 1, oxaloacetate condenses with acetyl-CoA to form citrate, which is catalyzed by...
need help with the blank please
Certain microorganisms with an incomplete citric acid cycle decarboxylate a-ketoglutarate to produce succinate semialdehyde. A dehydrogenase then converts succinate semialdehyde to succinate. Соо Coo CH, CH, NAD NADH CH, CH CH Co COO 000 -ketoglutarate Succinate Succinate semialdehyde These reactions can be combined with other standard citric acid cycle reactions to create a pathway from citrate to oxaloacetate that bypasses the reaction catalyzed by Dehydrogenase Tha reaction, a step that is accompanied by the...
Incorrect Question 3 0/1 pts Which enzyme is the link between the citric acid cycle and ATP formation? succinatethiokinase succinate dehydrogenase malate dehydrogenase citrate synthase isocitrate dehydrogenase
Acetyl COA + H2O Coo- o coo- Citrate synthase CH2 -OH -ooc— CH2 CH2 NADH + H+ COO- Oxaloacetate Coo- Citrate Aconitase Malate dehydrogenase NAD+ - Çoo- Çoo- ---OH -O00—-H HO-CH CH2 CH2 Coo- Malate Coo- Isocitrate Isocitrate lyase Malate synthase COO- COO- Coh CH2 Acetyl COA + H2O Ho Glyoxylate coo Succinate Figure 17.23 Biochemistry, Seventh Edition 2012 W. H. Freeman and Company Question 1 (10 pts) Using diagrams show the pathway that is used to convert succinate to...
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled in the diagram, reactions 1, 3, and 4 are regulation points in the citric acid cycle. oxaloacetate citrate synthase citrate NADH +Hi 7 malate dehydrogenase NAD malate aconitase 2 Which molecule inhibits reaction 1? isocitrate 7 fumarase NAD isocitrate dehydrogenase 3 NADH + H+ O citrate O NAD acetyl-CoA + CO2 fumarate C-ketoglutarate FADH succinate O dehydrogenase FAD O-ketoglutarate a dehydrogenase NAD + COA...
One of the early steps in the
citric acid cycle is the conversion of oxaloacetate to citrate..
see picture for more details
1. One of the early steps in the citric acid cycle is the conversion of oxaloacetate to citrate (see below). Propose a mechanism for this two step process using water and acidic/basic groups on the enzyme as needed (think NAC and NAS) OOC COO S- CoA. CH H20 O -C HO O -C CH citrate synthase CH CH2...
PLEASE ANSWER ALL PARTS. THANK YOU!
10. (12 pts) During cellular respiration the energy from oxidizing glucose to CO2 is used to synthesize ATP. NADH is an important intermediate that feeds electrons into the electron chain. A. (6 pts) Write down the net chemical equations (reactants products) that generate NADH in the citric acid cycle. Make sure to also name the enzymes that catalyze each individual reaction. B. (2 pts) All the dehydrogenases of glycolysis and the citric acid cycle...
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