10) Assume that a particular unusual phenotype is caused by an autosomal recessive allele. John has...

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10) Assume that a particular unusual phenotype is caused by an autosomal recessive allele. John has a brother who appears nor

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Answer 1

Answer #1

Autosomal inheritance pattern:
WT dominant allele = A
Mutant recessive allele = a
John = Aa
John's brother = Aa/AA
John's sister = aa
John's wife = Aa
John's daughter = aa

John's father = Aa
John's mother = Aa

See the image for the pedigree.

Johns father Johns mother A/a o A/a John Jane A/a A/a Johns brother A/a or AA Johns sister a/a a/a

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Answer 2

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