A student incorrectly calculated the net yield of ATP molecules from the complete oxidation of an...
A student incorrectly calculated the net yield of ATP molecules from the complete oxidation of an 18- carbon fatty acid to be 148 ATP. What did the student probably overlook? Justify your answer please.
Homework Answers
The student might have overlooked the number of ATPs consumed for the activation of fatty acid for lipolysis.
Stearic acid is a fatty acids with 18 carbons in its structure. The number of beta-oxidation rounds required are, (18/2)-1 = 8. Number of acetyl CoA produced are 18/2 = 9.
From beta-oxidation, 8 NADH are produced that correspond to 24 ATP (1 NADH = 3 ATP)
8 FADH2 are produce from Acetyl CoA = 16 ATP (1 FADH2 = 2 ATP)
Energy from Kreb's cycle: 27 NADH = 81 ATP
9 FADH2 = 18 ATP
9 ATP = 9ATP.
Total 148 ATP are produced and 2 ATP are consumed for the activation of fatty acid for lipolysis. So, the net ATP produced is, 146.
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