Question

The succinyl CoA to citrate pathway of the citric acid cycle is shown below. Identify the missing intermediates by dragging the item to the appropriate position. Then identify the missing cofactors below.

I have pulled up the "drop down" menu for the options for the "Cofactors"

Citrate H2C-CO2 H2C-co Succinyl CoA H2O AcCoA HO CO2 H2 GDP+P GTP CoA-SH CoA-SH CoA CO2 HO-C-H CH2 CO2 CO2 CO2 CH2 CH2 CO2 CO2 H-C-OH CH2 CO2 2 H CO2 CH2 CO2 factor A is: |Select answer Cofactor B is: NADH +Ht Cofactor C is: Cofactor D is Select answer FAD FADH2 NAD

Answer 1

Answer:

Succinyl CoA 02 Citrate H2O CO2 CO2 NAD+ CO2 AcCoA GDPP GTP FAD H CO2 HO-C-H HO-C-co2 -CO2 CH2 O CoA-SH CoA CH2 CO2 | NADH + CO2 CO2 FADH2 Succinate Fumarate Malate Oxaloacetate

Step 1: Conversion of succinyl CoA to Succinate by loosing CoA, which is replaced with a phosphate group.

Step 2: Succinate is oxidized to form fumarate by transfering two hydrogen atoms to FAD, which become FADH₂

Step 3: Fumate converts to malate with the help of water.

Step 4: Malate is oxidized to form oxaloacetate by utilizing hydrogen from NAD⁺ and form NADH +H⁺

Step 5: oxaloacetate is converted to citrate by joining with the acetyl CoA and releasing CoA group.