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If you clone a structural genes of the Yersinia pestis type III secretion system into harmless...

If you clone a structural genes of the Yersinia pestis type III secretion system into harmless E. coli, knowing that this E. coli strain will not become a human pathogen. Please give and explain the two causes for this.

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Answer #1

The type III secretion system is seen in Y.pestis and also in E.coli.

Since it is already mentioned that the E.coli is harmless, it indicates that the E.coli is not enteropathogenic or enterohemorrhagic. Only these kinds of E.coli can harm the human host.

The mode of action of both bacteria are different. Y.pestis mainly concentrates on immune cells of the host while E.coli concentrates on the intestine epithelium.

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