Homework Answers
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Answer is d, Acetyl-SCoA carboxylase
Acetyl-SCoA carboxylase is the enzyme which catalysed the carboxylation of acetyl-CoA to malonyl-CoA. Acetyl-CoA carboxylase responsible for fatty acid synthesis and degradation.
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11. Name the enryme catalyzing the following reaction a pyruvate carboxylase b propionyl-SCoA carboxylase c. PEP...
9. Which of the listed enzymes does not require biotin as coenzyme ?: a pyruvate carboxylase b. a...
9. Which of the listed enzymes does not require biotin as coenzyme ?: a pyruvate carboxylase b. acetyl-SCoA carboxylase c. propionyl-SCoA carboxylase d. PEP carboxykinase The source of acetyl-SCoA in the cytoplasm is: a carnitine b. oxaloacetate citrate d pyruvate e. lactate 10.
9. Which of the listed enzymes does not require biotin as coenzyme ?: a pyruvate carboxylase b. acetyl-SCoA carboxylase c. propionyl-SCoA carboxylase d. PEP carboxykinase The source of acetyl-SCoA in the cytoplasm is: a carnitine b. oxaloacetate...
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ?...
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? :a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. α-ketoglutarate dehydrogenase complex\}c. citrate synthase10. Name the enzyme catalyzing the following reaction:a. PEP carboxykinaseb. pyruvate kinasec. malic enzymed. pyruvate carboxylase11. Name the enzyme that catalyzes the reaction:glyoxylate +CH3CO-SCoA → malate + HSCoAa. malate synthaseb. succinate thiokinasec. aconitased. isocitrate
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ?...
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? : a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. a-ketoglutarate dehydrogenase complex e. citrate synthase 10. Name the enzyme catalyzing the following reaction: COOH + GTP - PEP + CO2 + GDP C=0 CH2 COOH a. PEP carboxykinase b. pyruvate kinase d. pyruvate carboxylase c. malic enzyme 11. Name the enzyme that catalyzes the reaction: glyoxylate + CH3CO-SCOA -- → malate +...
Biotin is a B-vitamin that is required for pyruvate carboxylase and acetyl-CoA carboxylase to function properly...
Biotin is a B-vitamin that is required for pyruvate carboxylase and acetyl-CoA carboxylase to function properly a) In a biotin deficiency, would you expect β-hydroxybutyrate concentration in blood to increase, decrease, or stay the same compared to a biotin sufficient control? b) How is pyruvate carboxylase involved in this effect on [BHB]? c) How is acetyl-CoA carboxylase involved in this effect on [BHB]?
1. Which enzyme is NOT part of the GNG process? a .Pyruvate kinase b. Pyruvate carboxylase...
1. Which enzyme is NOT part of the GNG process? a .Pyruvate kinase b. Pyruvate carboxylase c. Phosphoenolpyruvate carboxykinsase d. Glucose-6-phosphatase 2. Which molecule can NOT be derived from pyruvate in human? a. Oxaloacetate b. Acetyl CoA c. Lactate d. Ethanol 3. Which one of the following statements regarding the ruminant gluconeogenesis process is correct? a. It leads to net gain of ATP. b. It begins with propionate. c. It begins with lactate. d. It begins with pyruvate.
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d....
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d. lactic acidemia e. pellagra syrup urine disease b, phenylketonuria c. galactosemia 10. Chemical modification by phosphorylation of pyruvate dehydros a. deactivates the enzyme b. activates the enzyme lation of pyruvate dehydrogenase complex : 17. Pyruvate carboxylase is positively ated through the allosteric mechanism by : a. ATP b. NADH c. Acetyl-SCOA d. TPP e. Biotin 18. Which of the listed coenzymes does not particip...
The primary regulatory point of gluconeogenesis is____? a. glucose-6-phosphatase b. fructose-1,6-biphosphatase c. fuctose-2,6-biphosphatase d. pyruvate carboxylase...
The primary regulatory point of gluconeogenesis is____? a. glucose-6-phosphatase b. fructose-1,6-biphosphatase c. fuctose-2,6-biphosphatase d. pyruvate carboxylase (wrong answer) e. PEP carboxykinase Please explain why pyruvate carboxylase is wrong (isn't it one of the regulatory points, is it wrong because it isn't the primary one? and if so, how do you know what the primary one is?) and state the right answer and an explanation as to why.
5.The following reaction has a ΔG°'--61.9 kJ/mol at 25°C, Phosphoenolpyruvate (PEP) +H2O Pyruvate + Inorganic Phosphate...
5.The following reaction has a ΔG°'--61.9 kJ/mol at 25°C, Phosphoenolpyruvate (PEP) +H2O Pyruvate + Inorganic Phosphate (Pi) (a) Is the reaction favorable under standard biochemical conditions? Explain your answer. (b) What is the equilibrium constant (K) of this reaction at 25°C? In cells the direct hydrolysis of PEP rarely occurs. Rather, the hydrolysis of PEP and the reverse hydrolysis of ATP are coupled (c) w rite out the coupled reaction and determine its ΔG at 25°C The hydrolysis of ATP...
Pyruvate kinase catalyzes the last reaction in the glycolytic pathway: phosphoenolpyruvate (PEP) + ADP --> pyruvate...
Pyruvate kinase catalyzes the last reaction in the glycolytic
pathway:
phosphoenolpyruvate (PEP) + ADP --> pyruvate + ATP
There are four different mammalian forms of pyruvate kinase. All
catalyze the same reaction, but they differ in their response to
the glycolytic metabolite fructose-1,6-bisphosphate (F16BP).
The activity of two forms of pyruvate kinase was measured at
various concentrations of PEP, as shown below. Activity was
measured in the presence (blue circles) and absence (red circles)
of F16BP.
Pyruvate Kinase Form 1...
Pyruvate kinase catalyzes the last reaction in the glycolytic pathway: phosphoenolpyruvate (PEP) + ADP --> pyruvate...
Pyruvate kinase catalyzes the last reaction in the glycolytic
pathway:
phosphoenolpyruvate (PEP) + ADP --> pyruvate + ATP
There are four different mammalian forms of pyruvate kinase. All
catalyze the same reaction, but they differ in their response to
the glycolytic metabolite fructose-1,6-bisphosphate (F16BP).
The activity of two forms of pyruvate kinase was measured at
various concentrations of PEP, as shown below. Activity was
measured in the presence (blue circles) and absence (red circles)
of F16BP.
Pyruvate Kinase Form 1...
9. Which of the listed enzymes does not require biotin as coenzyme ?: a pyruvate carboxylase b. acetyl-SCoA carboxylase c. propionyl-SCoA carboxylase d. PEP carboxykinase The source of acetyl-SCoA in the cytoplasm is: a carnitine b. oxaloacetate citrate d pyruvate e. lactate 10.
9. Which of the listed enzymes does not require biotin as coenzyme ?: a pyruvate carboxylase b. acetyl-SCoA carboxylase c. propionyl-SCoA carboxylase d. PEP carboxykinase The source of acetyl-SCoA in the cytoplasm is: a carnitine b. oxaloacetate...
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? :a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. α-ketoglutarate dehydrogenase complex\}c. citrate synthase10. Name the enzyme catalyzing the following reaction:a. PEP carboxykinaseb. pyruvate kinasec. malic enzymed. pyruvate carboxylase11. Name the enzyme that catalyzes the reaction:glyoxylate +CH3CO-SCoA → malate + HSCoAa. malate synthaseb. succinate thiokinasec. aconitased. isocitrate
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? : a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. a-ketoglutarate dehydrogenase complex e. citrate synthase 10. Name the enzyme catalyzing the following reaction: COOH + GTP - PEP + CO2 + GDP C=0 CH2 COOH a. PEP carboxykinase b. pyruvate kinase d. pyruvate carboxylase c. malic enzyme 11. Name the enzyme that catalyzes the reaction: glyoxylate + CH3CO-SCOA -- → malate +...
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d. lactic acidemia e. pellagra syrup urine disease b, phenylketonuria c. galactosemia 10. Chemical modification by phosphorylation of pyruvate dehydros a. deactivates the enzyme b. activates the enzyme lation of pyruvate dehydrogenase complex : 17. Pyruvate carboxylase is positively ated through the allosteric mechanism by : a. ATP b. NADH c. Acetyl-SCOA d. TPP e. Biotin 18. Which of the listed coenzymes does not particip...
5.The following reaction has a ΔG°'--61.9 kJ/mol at 25°C, Phosphoenolpyruvate (PEP) +H2O Pyruvate + Inorganic Phosphate (Pi) (a) Is the reaction favorable under standard biochemical conditions? Explain your answer. (b) What is the equilibrium constant (K) of this reaction at 25°C? In cells the direct hydrolysis of PEP rarely occurs. Rather, the hydrolysis of PEP and the reverse hydrolysis of ATP are coupled (c) w rite out the coupled reaction and determine its ΔG at 25°C The hydrolysis of ATP...
Pyruvate kinase catalyzes the last reaction in the glycolytic
pathway:
phosphoenolpyruvate (PEP) + ADP --> pyruvate + ATP
There are four different mammalian forms of pyruvate kinase. All
catalyze the same reaction, but they differ in their response to
the glycolytic metabolite fructose-1,6-bisphosphate (F16BP).
The activity of two forms of pyruvate kinase was measured at
various concentrations of PEP, as shown below. Activity was
measured in the presence (blue circles) and absence (red circles)
of F16BP.
Pyruvate Kinase Form 1...
Pyruvate kinase catalyzes the last reaction in the glycolytic
pathway:
phosphoenolpyruvate (PEP) + ADP --> pyruvate + ATP
There are four different mammalian forms of pyruvate kinase. All
catalyze the same reaction, but they differ in their response to
the glycolytic metabolite fructose-1,6-bisphosphate (F16BP).
The activity of two forms of pyruvate kinase was measured at
various concentrations of PEP, as shown below. Activity was
measured in the presence (blue circles) and absence (red circles)
of F16BP.
Pyruvate Kinase Form 1...
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