Question

Explain why the most polar compound layer stays in the organic layer, while the less polar compounds go into the aqueous phase. (This is for a liquid-liquid extraction)

The most polar compund is caffeine and the solvent is ethyl acetate. I know it has to do with the caffeine not being able to deprotonate but I’m still confused and would like more information on why is can’t deprotonate.

Answer 1

And most polar compound layer stays in organic layer while less polar compound go into the aqueousphase because the organic layer contain a sel vent (Cha Ug ok ether) that is insoluble in water. The falar compounds are insoluble in aqueous phase (120) because even though their functional gps may have dipoles which make them polar , they usually have large R genoups that are made of carbon, thus making the whole thing insoluble in water (aquous phax) and mastering the solubility of functional g h itself. we can separate such compounds from insoluble organic layer by making them changed te by adding and I base to them to protonate (deprotonate the functional groups. Aftu addr of acid di base, you will form new aqueous layer that contain compound you were buying to antract. - Caffeine is a fellau molecule thus it has hy arophobic portions and dichloromethane is ethyl acetate polar organic solvent caffeine is not soluble in water at room temperature as enplained above the reason. Thus it migrates to organic layer.