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Acyl CoA Synthetase is an enzyme that requires ATP to function. Why can acyl-CoA synthetase make...

Acyl CoA Synthetase is an enzyme that requires ATP to function. Why can acyl-CoA synthetase make ATP, when it consumes ATP?

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Answer #1

The enzyme acetyl CoA synthetase is required for the synthesis of acetyl CoA. In presence of this enzyme CoA and acetate reacts to form acetyl CoA. But this reaction requires energy means ATP. Now the formed Acetyl CoA participates in the TCA cycle or krebs cycle. In the TCA cycle, the stored energy in the body in the form of carbohydrate, protein, fat undergoes oxidation to release ATP. So ATP is released.

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