Assuming the standard intake values in your text, and assuming the worst case absorption factor, calculate the air and water concentration standards that would yield the following specified risks from the following specified substances:
a. Benzene in drinking water (μg/L) at a lifetime acceptable risk of l×l0-5. Assume a cancer slope factor of 0.015 kg.d/mg.Answer: 24 μg/Lb.
b.Trichloroethylene in air (μg/m3) at a lifetime acceptable risk of l×l0-6. Slope factor for inhalation = 0.029 kg.d/mg.Answer: 12.6 μg/m3
Assuming the standard intake values in your text, and assuming the worst case absorption factor, calculate...
1. The drinking water standard for tetrachloroethylene is 0.005 mg/L, The potency factor for tetrachloroethylene is 5.1*10^-2 (mg/kg-day)^-1. What lifetime risk would this pose? Assume 30 year exposure for 350 days per year. 2. •Suppose a 70-kg man is exposed to 0.1 mg/m3 o etrachloroethylene in the air at his workplace. If he inhales 1m3/hr, 8 hours per day, 5 days per week, 50 weeks per year, for 30 years, and if tetrachloroethylene has an absorption factor of 90 percent...
Chronic dally irve. It can also be FIGURE 4.10 The potency factor is the slope of the dose-response curve. It thought of as the risk that corresponds to a chronic daily intake of 1 mg/kg-da Potency Factory Inhalation Row (mg/kg-dayi 50 2.9 x 10-2 6.11 6.1 8.1 x 10-2 - 41 TABLE 4.9 Toxicity Data for Selected Potential Carcinogens Potency Factor Oral Route Category (mg/kg-day) Chemical 1.75 Arsenic 2.9 X 10-2 Benzene 11.5 Benzol(a)pyrene Cadmium 0.13 Carbon tetrachloride 6.1 X...