Enzyme |
Source |
Substrates |
Products |
Pancreatic amylase |
Pancreatic acinar cells |
Starches |
Maltose, maltotriose, and alpha dextrins. |
Trypsin |
Pancreatic acinar cells |
Proteins |
Peptides |
chymotrypsin |
Pancreatic acinar cells |
Proteins |
Peptides |
Elastase |
Pancreatic acinar cells |
Proteins |
Peptides |
Carboxypeptidase |
Pancreatic acinar cells |
Amino acid at carboxyl end of peptides |
Amino acids and Peptides |
Pancreatic lipase |
Pancreatic acinar cells |
Triglycerides |
Fatty acids and monoglycerides |
Ribonuclease |
Pancreatic acinar cells |
Ribonucleic acid |
Nucleotides |
Deoxyribonuclease |
Pancreatic acinar cells |
Deoxyribonucleic acid |
Nucleotides |
total 8 hydrolytic enzymes.
What is a lysosome? What is its function? b) How are hydrolytic enzymes selected and transported (trafficked) into a lysosome? c) What is a lysosomal storage disease? d) Name ONE lysosomal storage disease and describe the genetic defect that leads to the disease.
1. Human lysosomes contain hydrolytic enzymes that are activated at a pH of 4.5-5.0. Which of the following factors could alter the structure integrity of a hydrolytic enyzme causing a loss of function? (MULITPLE ANSWERS – select all that apply) a. temperature below body temperature b. pH above 5.0 c. pH below 4.5 d. temerature above body temperature e. genetic mutation in hydrolytic enzyme gene
Which of the following is NOT true about lysosomes? Hydrolytic enzymes found in lysosomes are active in environments with low [H+]. Lysosomes are the main site for intracellular digestion. All of the above are true. The low pH of lysosomes is maintained by active transport of H+ from the cytosol.
(5) Describe the chemical properties of zinc that are relevant to its catalytic role in hydrolytic enzymes (6) The protein liver alcohol dehydrogenase (LADH) contains two zinc sites. The first has 4 cysteine ligands and the second has 2 histidine, 2 cysteine and one water ligand. Explain why there is a difference and how the difference relate to the function of LADH?
(5) Describe the chemical properties of zinc that are relevant to its catalytic role in hydrolytic enzymes (6)...
Each day, the pancreas produces up to 1.5 L of pancreatic juices that enter the duodenum via the pancreatic duct. The pancreatic juices consist of water, salts, bicarbonate ions, and digestive enzymes. Bicarbonate ion raises the pH of the acidic chyme from the stomach, stopping the active ity of pepsin and allowing the pancreatic and intestinal enzymes to function. The various pancre. atic enzymes and their substrates are listed in Table 10.2. Table 10.2 Various enzymes produced by the pancreas...
involved in digestion. 20- Lysosomes are vacuoles of a granules b. lipids c. hydrolytic enzymes d. nonc of the above 21- The Golgi body is involved in a) Protein production b) Cell division c) Intra cellular digestion d) Packaging and secretion of materials 22- Some factors to consider when choosing an antimicrobial agent are a. Cost storage b. Toxicity c Residue buildup reaction with organic matter d. All of the above 23-A sterile item is free of a. bacteria b....
Role of the Pancreas Key: pancreas glucagon endocrine insulin exocrine Type II diabetes Type I diabetes ________________ is gland located under the stomach that produces insulin and glucagon The pancreas has an _______________ function to secrete sodium bicarbonate and digestive enzymes and also an ________________function to secrete insulin and glucagon hormones _____________ is the only hormone that causes blood sugar levels to lower as it signals cells to take up glucose for their energy source and signals the liver...
Explain how exo-enzymes produced by bacteria which digest different macro-molecules in the surrounding environment, won’t digest these molecules inside the bacterial cells?
how many grams of CO2 will be produced if 3490. grams
of iron is also produced?
Iron ore is converted to iron by heating it with coal (carbon) and oxygen according to the following unbalanced equation: 2_Fe2O3(s) + 4_C(s) + I_02(g) — 4 Fe(s) +4 CO2(g) First, balance the equation. (2 points) Then answer the following questions. a. How many grams of CO, will be produced if 3940. g of iron is also produced? (3 points) b. How many grams...
What role does the pancreas play during digestion? What part of the pancreas carries out this role? How does this vary across the glands themselves?