Insulin is a protein hormone secreted by pancreatic beta cells. Diagram the pathway that is used...
Insulin is a protein hormone secreted by pancreatic beta cells. Diagram the pathway that is used to synthesize and (secrete) export proteins. Include the amount of detail that helps you properly review the endomembrane system.
Homework Answers
Ans. Insulin composed of two chains held together by disulfide bonds. Insulin is synthesized in beta cells in the pancreas. The insulin mRNA's translation takes place and forms a single chain precursor called preproinsulin and when it enters the endoplasmic reticulum, its signal peptide is removed which generates proinsulin.
There are three domains of proinsulin- an amino terminal
B-chain, a carboxy-terminal A chain and a C peptide in the middle
which connects the other two chains. In ER, endopeptidases are
present which excise the C peptide which generates the insulin.
Insulin and free C peptide are packaged in the golgi in form of
secretory granules and gets accumulated in the cytoplasm. Then
insulin is secreted from the cell by the process of
exocytosis.
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Insulin is a protein hormone secreted by pancreatic beta cells.
Diagram the pathway that is used...
Insulin is a protein which is synthesized and secreted by pancreatic cells. Describe the path insulin...
Insulin is a protein which is synthesized and secreted by pancreatic cells. Describe the path insulin proteins would take through the cell from it's transcription in the nucleus to its secretion into the extracellular matrix. Describe the structure and function of all the organelles involved and describe what happens to insulin as it moves through endomembrane system. (10 marks)
Insulin is a hormone made and secreted by the beta cells in the pancreas. You have...
Insulin is a hormone made and secreted by the beta cells in the pancreas. You have generated various beta-cell mutant cell lines as described below. Explain whether the mutation will have an effect on the insulin secretion. If so, what step(s) of the secretory pathway is likely to be affected by the mutation? Explain your answers. Cell line A: A small GTPase Arf1 (functions on Golgi membrane) is mutated that the GTPase domain of the protein is inactive Cell line...
35. Insulin is a peptide (protein) hormone secreted by B-cells located in the pancreas. To be...
35. Insulin is a peptide (protein) hormone secreted by B-cells located in the pancreas. To be protein) hormone used to regulate the level of glucose in the bloodstream. It is produced and performed. cated in the pancreas. To better understand how insulin is secreted, the following experiments were a. The mature me mature mRNA for insulin encodes a protein that is 110 amino acids in length. If the genes t is 110 amino acids in length. If the gene is...
6. Islet amyloid polypeptide (IAPP), often called amylin, is a peptide hormone that is co-secreted with...
6. Islet amyloid polypeptide (IAPP), often called amylin, is a peptide hormone that is co-secreted with insulin from pancreatic B-cells. In combination, insulin and amylin regulate blood glucose levels. In this signaling process, amylin participates in slowing gastric emptying and promoting satiety, helping to prevent spikes in blood glucose levels. Using your knowledge of protein sequencing and proteomics, answer the questions below related to amylin. A. Islet amyloid polypeptide (IAPP, amylin) is produced by processing of a precursor protein called...
MATCHING Terec a adrenal giand E. glucagon g hormone h. insulin k thymus L thyroid gland mthyroxi...
MATCHING Terec a adrenal giand E. glucagon g hormone h. insulin k thymus L thyroid gland mthyroxine n tropic hormone b. aldosterone beta cells d. calcitonin e endocrine gland osytocin For each of these definitions, select the correct matching term from the list above. 1. A hormone produced by the hypothalamus and released by the postesior lobe of che pituitary causes the uterus to contract and stimulates the release of milk from the mammary glands. 2 A hoemone secreted by...
Required: I need to paraphrase the answer because it is plagiarized. . Question: What is the...
Required: I need to paraphrase the answer because it is plagiarized. . Question: What is the function of beta cells in the pancreas? Answer: Beta cells (β cells) are a type of cell found in pancreatic islets that synthesize and secrete insulin and amylin. Beta cells make up 50–70% of the cells in human islets. In patients with type I or type II diabetes, beta-cell mass and function are diminished, leading to insufficient insulin secretion and hyperglycemia. The pancreas is...
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???
DeepSea Explorer brings some sample near a hydrothermal vent on the seabed some 1000-meter deep. Upon examination with a light microscope, a unicellular star-shaped microorganism was discovered in the sample and cells were collected and their chemical compositions were analyzed. a) After analysis, scientists discover that these cells contain DNA, RNA, proteins and phospholipids Based on these results, you can conclude the organism is made of cells of Prokaryotic 1) Eukaryotic i) Cannot be determined b) Explain your reasoning...
Question 15 (2 points) ✓ Saved Select all of the following that are part of the...
Question 15 (2 points) ✓ Saved Select all of the following that are part of the extracellular matrix. Actin Fibronectin Myosin Collagen Question 16 (4 points) ✓ Saved Please put the following activities of translation initiation in order from first to last. 1 v Small subunit of ribosome binds to mRNA 4 v A-site is open 2 tRNA with anticodon UAC binds to mRNA codon AUG 3 large subunit of ribosome binds to mRNA Question 17 (2 points) ✓ Saved...
In part A, yes you should reconstitute the full-length protein sequence from the fragments. However, you...
In part A, yes you should reconstitute the full-length protein
sequence from the fragments. However, you do not need to write out
the amino acid sequence - you can just provide the order of the
fragment numbers (from either set of fragments). For
example (and this is not the answer), you could say:
"Using the Pro-IAPP fragment set, starting from the N-terminus, the
fragment order is '5-4-6-3-2-1' " and that would fully address the
question.
In part B, the hint...
A. Match the following cells rith their meanings below: hematopoietic stem cell lymphocyte mопосyte basophil cosinophil...
A. Match the following cells rith their meanings below: hematopoietic stem cell lymphocyte mопосyte basophil cosinophil erythyocyte neutrophil platelet 1. red blood cell white blood cell: phagocyte and precursor of a macrophage 2. 3. thrombocyte bone marrow cell; gives rise to many types of blood cells 4. 5. leukocyte formed in lymph tissue; produces antibodies 6. leukocyte with dense reddish granules; associated with allergic reactions 7. leukocyte (poly) formed in bone marrow and having neutral-staining granules 8. leukocyte whose granules...
Insulin is a protein which is synthesized and secreted by pancreatic cells. Describe the path insulin proteins would take through the cell from it's transcription in the nucleus to its secretion into the extracellular matrix. Describe the structure and function of all the organelles involved and describe what happens to insulin as it moves through endomembrane system. (10 marks)
35. Insulin is a peptide (protein) hormone secreted by B-cells located in the pancreas. To be protein) hormone used to regulate the level of glucose in the bloodstream. It is produced and performed. cated in the pancreas. To better understand how insulin is secreted, the following experiments were a. The mature me mature mRNA for insulin encodes a protein that is 110 amino acids in length. If the genes t is 110 amino acids in length. If the gene is...
6. Islet amyloid polypeptide (IAPP), often called amylin, is a peptide hormone that is co-secreted with insulin from pancreatic B-cells. In combination, insulin and amylin regulate blood glucose levels. In this signaling process, amylin participates in slowing gastric emptying and promoting satiety, helping to prevent spikes in blood glucose levels. Using your knowledge of protein sequencing and proteomics, answer the questions below related to amylin. A. Islet amyloid polypeptide (IAPP, amylin) is produced by processing of a precursor protein called...
MATCHING Terec a adrenal giand E. glucagon g hormone h. insulin k thymus L thyroid gland mthyroxine n tropic hormone b. aldosterone beta cells d. calcitonin e endocrine gland osytocin For each of these definitions, select the correct matching term from the list above. 1. A hormone produced by the hypothalamus and released by the postesior lobe of che pituitary causes the uterus to contract and stimulates the release of milk from the mammary glands. 2 A hoemone secreted by...
???
DeepSea Explorer brings some sample near a hydrothermal vent on the seabed some 1000-meter deep. Upon examination with a light microscope, a unicellular star-shaped microorganism was discovered in the sample and cells were collected and their chemical compositions were analyzed. a) After analysis, scientists discover that these cells contain DNA, RNA, proteins and phospholipids Based on these results, you can conclude the organism is made of cells of Prokaryotic 1) Eukaryotic i) Cannot be determined b) Explain your reasoning...
Question 15 (2 points) ✓ Saved Select all of the following that are part of the extracellular matrix. Actin Fibronectin Myosin Collagen Question 16 (4 points) ✓ Saved Please put the following activities of translation initiation in order from first to last. 1 v Small subunit of ribosome binds to mRNA 4 v A-site is open 2 tRNA with anticodon UAC binds to mRNA codon AUG 3 large subunit of ribosome binds to mRNA Question 17 (2 points) ✓ Saved...
In part A, yes you should reconstitute the full-length protein
sequence from the fragments. However, you do not need to write out
the amino acid sequence - you can just provide the order of the
fragment numbers (from either set of fragments). For
example (and this is not the answer), you could say:
"Using the Pro-IAPP fragment set, starting from the N-terminus, the
fragment order is '5-4-6-3-2-1' " and that would fully address the
question.
In part B, the hint...
A. Match the following cells rith their meanings below: hematopoietic stem cell lymphocyte mопосyte basophil cosinophil erythyocyte neutrophil platelet 1. red blood cell white blood cell: phagocyte and precursor of a macrophage 2. 3. thrombocyte bone marrow cell; gives rise to many types of blood cells 4. 5. leukocyte formed in lymph tissue; produces antibodies 6. leukocyte with dense reddish granules; associated with allergic reactions 7. leukocyte (poly) formed in bone marrow and having neutral-staining granules 8. leukocyte whose granules...
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