Explain why a mutation in only one of two copies of a proto-oncogene in a diploid cell can promote the development of cancer (5 points), whereas both copies of a tumor-suppressor gene need to be mutated to do likewise (5 points).
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Explain why a mutation in only one of two copies of a proto-oncogene in a diploid...
Q1)canser start when: 1:only tumor suppressor gene is mutated. 2:only proto-oncogene is mutated. 3:proto-oncogene and tumor suppressor gene are mutated at the sane time 4:proto-oncogene and tumor suppressor gene are not mutated at the sane time . which is correct ?
Explain why a gain-of-function mutation to a proto-oncogene (or its promoter) may be associated with increased risk of cancer. (b) Explain why a loss-of-function mutation to a tumor suppressor gene may be associated with increased risk of cancer.
Indicate whether each of the following descriptions applies to an oncogene, a proto-oncogene, or a tumor suppressor gene. Some descriptions may apply to more than one of these gene types. Drag the gene types on the left to the appropriate blanks on the right to match the descriptions. Gene types can be used once, more than once, or not at all. Reset Help oncogene - gene(s) whose presence can cause cancer. proto-oncogene -gene(s) whose absence can cause cancer. tumor suppressor...
Cancer and Gene Regulation Why is a cell cycle control system needed for cell division? What happens when cells do NOT respond to the cell cycle control system and divide excessively? Tumor Proto-oncogeno (for protein that stimulates coll division) 6 Y DNA Benign Tumor= Mutation withln a control region of DNA Malignant Tumor Mutated promoter Metastasis Normal growth-stimulating protein in excess Oncogene Tumor-Suppressor Genes Proto-oncogene utled tara gese Samor-auppresr gane Many proto-oncogenes code for growth factors /Deletive nonimenig Normel grewt...
13. Which of these statements is TRUE? a. Cancer cells usually have more than one mutation. . Proto-oncogenes are normal genes that code for proteins that cause cells to undergo apoptosis (programmed cell death) c. Cancer usually involves a gain-of-function mutation in a tumor suppressor gene d. Cancer usually involves a loss-of-function mutation proto-oncogene
Given that TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene? Given that is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without...
Label the following as either proto-oncogene, oncogene or tumor suppressor 3. A gene that initiates apoptosis when DNA damage occurs a. b. A gene that initiates the transition from G1 to S phase A gene that inhibits the transition from G1 to S phase c. d. A gene that promotes cell growth, combined with a hyperactive promoter How would methylation of the promoter of the gene in question 3c affect the cell? Be specific using what you know about the...
1. Viral integration into the cellular genome may convert a proto-oncogene into a transforming oncogene 2. Immunosuppressive drugs used to prevent graft rejection include drugs (like Imuran) that result in generalized suppression of all dividing cells and drugs that target T cells (like cyclosporine A) 3. IFNα has a direct antitumor effect, while TNFα has an indirect cytotoxic effect on tumor cells 4.Oncogenes are unique genes of a normal cell that only function to promote cell transformation. 5. Attributes of...
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Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...
T/F 1. Viral integration into the cellular genome may convert a proto-oncogene into a transforming oncogene 2. Immunosuppressive drugs used to prevent graft rejection include drugs (like Imuran) that result in generalized suppression of all dividing cells and drugs that target T cells (like cyclosporine A) 3. IFNα has a direct antitumor effect, while TNFα has an indirect cytotoxic effect on tumor cells 4. Oncogenes are unique genes of a normal cell that only function to promote cell transformation. 5. Attributes of tumor cells include lack...