Imagine that there is a mechanism that allows protons to re-enter the mitochondrial matrix without the...
Imagine that there is a mechanism that allows protons to re-enter the mitochondrial matrix without the coupled phosphorylation of ADP. What would happen to the energy associated with the proton re-entering?
Homework Answers
If protons can re enter mitochondrial matrix without phosphorylation of ADP to ATP, then there will be a disasterous effect on cell metabolism. When protons moves through F0F1 ATPase , it moves the F0F1 ATPase like a water wheel and due to this movement, phosphorylation of ADP to ATP occurs. But if protons moves into the matrix by any other way, concentration gradient will gradually lost and ultimately proton movement will cease. This will affect ATP production by F0F1ATPase and due to lack of ATP in the cell, the cell will eventually die.
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Imagine that there is a mechanism that allows protons to
re-enter the mitochondrial matrix without the...
The high concentration of protons in the inner mitochondrial space relative to the mitochondrial matrix represents...
The high concentration of protons in the inner mitochondrial space relative to the mitochondrial matrix represents what kind of energy? , energy is released and exploited to combine ADP and J As protons flow through the inorganic phosphate to form ATP.
6) What protein complex in the inner mitochondrial membrane allows protons to return to the matrix?...
6) What protein complex in the inner mitochondrial membrane allows protons to return to the matrix? ONADH dehydrogenase FoF1 porin electron transport carriers cytochrome 47) Which of the following compounds inhibits the pyruvate dehydrogenase (2pts) complex? O FAD NAD+ □ ADP acetyl COA 48) The acetyl group of acetyl CoA is transferred to oxaloacetate by the enzyme citrate synthase. OTrue (2pts) False
8. The movement of protons out of the mitochondrial matrix establishes an electrochemical H gradient across...
8. The movement of protons out of the mitochondrial matrix establishes an electrochemical H gradient across the inner mitochondrial membrane. The electrochemical potential of this gradient is harnessed to synthesize ATP. This is known as the (A) Hydrophobic effect IqChemiosmotic theory (B) Acid catalysis (0) Michaelis-Menten mechanism _9. Which of the following statements about mitochondria and their lon and metabolite transporters is FALSE? (A) Controlled impermeability of the inner mitochondrial membrane to most ions and metabolites allows for the generation...
certain drugs are commonly used to study mitochondrial respiration. These drugs include Rotenone, oligomycin, and the...
certain drugs are commonly used to study mitochondrial respiration. These drugs include Rotenone, oligomycin, and the mitochondrial uncoupler dinitrophenol. Rotenone inhibits the transfer of electrons from Complex 1 to Uniquinone, oligomycin inhibits Complex 5/ATP synthase by preventing the re-entry of protons into the matrix, and Dinitrophenol leads to the uncoupling of oxidation from phosphorylation of ADP (meaning that less ATP is produced). If you were interested in studying the ATP production through glycolysis only, which of these inhibitors would be...
QUESTIONS 0.1 points Save Answer What is chemiosmosis? ATP synthase rotating to add a phosphate to...
QUESTIONS 0.1 points Save Answer What is chemiosmosis? ATP synthase rotating to add a phosphate to ADP - ATP All of these contribute to chemiosmosis Proton gradient in the inner membrane space causing protons to enter into the matrix causing ATP synthase to convert ADP to ATP An electrical gradient causes protons to enter the matrix causing ATP synthase to convert ADP to ATP QUESTION 10 0.1 points Save Aswer What is substrate level phosphorylation? Using Water and CO2 to...
Q2. The release of ATP by the beta subunit is most directly dependent on: Select ONE...
Q2.
The release of ATP by the beta subunit is most directly
dependent on:
Select ONE option:
1. the flow of protons from the intermembrane space to the
matrix.
2. the rotation of the c-ring in the membrane.
3. the passage of electrons along the electron transport
chain.
4. a conformational change in the beta subunit.
Q3.
What defines the direction of rotation of the c-ring in the F0
complex?
(Select ALL that apply.)
1. Amino acids side chains in...
What process uses ATP to create glucose? O ATP synthase electron transport chain O gluconeogenesis O...
What process uses ATP to create glucose? O ATP synthase electron transport chain O gluconeogenesis O citric acid cycle Question 11 (2 points) What would expect to happen in mitochondria that have fewer cristae Increased proton motive force Decreased oxygen usage increased ATP to ADP conversion O No change in mitocondrial funciton Question 12 (2 points) What is one example of when energy molecules/electron carriers are produced during the citric acid cycle? O conversion of succinate to fumarate O addition...
21) Which process in eukaryotic cells will normally proceed whether O2 is present or absent? A)...
21) Which process in eukaryotic cells will normally proceed whether O2 is present or absent? A) oxidative phosphorylation B) glycolysis C) Krebs cycle D) electron transport 22) The direct energy source that drives ATP synthesis during respiratory oxidative phosphorylation is A) thermodynamically favorable transfer of phosphate from glycolysis and Krebs cycle intermediate molecules of ADP. B) the thermodynamically favorable flow of electrons from NADH to the mitochondrial electron transport carriers. C) the final transfer of electrons to oxygen. D) the...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring compound that binds to protein complex IV of the mitochondrial electron transport chain and prevents transfer of electrons from the protein. Metformin: At the cellular level, chemically synthesized metformin, a drug commonly prescribed for Type 2 diabetes, inhibits mitochondrial respiration by blocking complex I. Dinitrophenol: Dinitrophenol is a metabolic poison that can be sold legally as a pesticide. Although it is lethal to humans,...
6) Explain what would happen if someone took the drug DNP (dinitrolphenol). DNP allows H+ ions...
6) Explain what would happen if someone took the drug DNP (dinitrolphenol). DNP allows H+ ions to flow down the concentration gradient and across the inner mitochondrial membrane without going through the ATP Synthase. Why would this be a problem for Cell Respiration? You may want to refer to your diagram of the ETC to help you. Answer this in 3-5 well crafted sentences. 7) Describe what happens to the free energy of the carbon molecules through Cell Respiration. Your...
The high concentration of protons in the inner mitochondrial space relative to the mitochondrial matrix represents what kind of energy? , energy is released and exploited to combine ADP and J As protons flow through the inorganic phosphate to form ATP.
6) What protein complex in the inner mitochondrial membrane allows protons to return to the matrix? ONADH dehydrogenase FoF1 porin electron transport carriers cytochrome 47) Which of the following compounds inhibits the pyruvate dehydrogenase (2pts) complex? O FAD NAD+ □ ADP acetyl COA 48) The acetyl group of acetyl CoA is transferred to oxaloacetate by the enzyme citrate synthase. OTrue (2pts) False
8. The movement of protons out of the mitochondrial matrix establishes an electrochemical H gradient across the inner mitochondrial membrane. The electrochemical potential of this gradient is harnessed to synthesize ATP. This is known as the (A) Hydrophobic effect IqChemiosmotic theory (B) Acid catalysis (0) Michaelis-Menten mechanism _9. Which of the following statements about mitochondria and their lon and metabolite transporters is FALSE? (A) Controlled impermeability of the inner mitochondrial membrane to most ions and metabolites allows for the generation...
QUESTIONS 0.1 points Save Answer What is chemiosmosis? ATP synthase rotating to add a phosphate to ADP - ATP All of these contribute to chemiosmosis Proton gradient in the inner membrane space causing protons to enter into the matrix causing ATP synthase to convert ADP to ATP An electrical gradient causes protons to enter the matrix causing ATP synthase to convert ADP to ATP QUESTION 10 0.1 points Save Aswer What is substrate level phosphorylation? Using Water and CO2 to...
Q2.
The release of ATP by the beta subunit is most directly
dependent on:
Select ONE option:
1. the flow of protons from the intermembrane space to the
matrix.
2. the rotation of the c-ring in the membrane.
3. the passage of electrons along the electron transport
chain.
4. a conformational change in the beta subunit.
Q3.
What defines the direction of rotation of the c-ring in the F0
complex?
(Select ALL that apply.)
1. Amino acids side chains in...
What process uses ATP to create glucose? O ATP synthase electron transport chain O gluconeogenesis O citric acid cycle Question 11 (2 points) What would expect to happen in mitochondria that have fewer cristae Increased proton motive force Decreased oxygen usage increased ATP to ADP conversion O No change in mitocondrial funciton Question 12 (2 points) What is one example of when energy molecules/electron carriers are produced during the citric acid cycle? O conversion of succinate to fumarate O addition...
21) Which process in eukaryotic cells will normally proceed whether O2 is present or absent? A) oxidative phosphorylation B) glycolysis C) Krebs cycle D) electron transport 22) The direct energy source that drives ATP synthesis during respiratory oxidative phosphorylation is A) thermodynamically favorable transfer of phosphate from glycolysis and Krebs cycle intermediate molecules of ADP. B) the thermodynamically favorable flow of electrons from NADH to the mitochondrial electron transport carriers. C) the final transfer of electrons to oxygen. D) the...
Inhibitors of Oxidative Phosphorylation The following chemicals inhibit oxidative phosphorylation: Cyanide: Cyanide is a naturally occurring compound that binds to protein complex IV of the mitochondrial electron transport chain and prevents transfer of electrons from the protein. Metformin: At the cellular level, chemically synthesized metformin, a drug commonly prescribed for Type 2 diabetes, inhibits mitochondrial respiration by blocking complex I. Dinitrophenol: Dinitrophenol is a metabolic poison that can be sold legally as a pesticide. Although it is lethal to humans,...
6) Explain what would happen if someone took the drug DNP (dinitrolphenol). DNP allows H+ ions to flow down the concentration gradient and across the inner mitochondrial membrane without going through the ATP Synthase. Why would this be a problem for Cell Respiration? You may want to refer to your diagram of the ETC to help you. Answer this in 3-5 well crafted sentences. 7) Describe what happens to the free energy of the carbon molecules through Cell Respiration. Your...
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