You are studying an enzymatic reaction catalyzed by Lysozyme, an enzyme present in human mucous. Lysozyme is one of the first lines of defense against bacterial infection because it catalyzes the hydrolysis of glycosidic bonds present in bacterial cell walls. You discover that the overall DG for the reaction that you have set up containing peptidoglycan (a carbohydrate polymer that is a component of bacterial cell walls) and 5 nM Lysozyme is -50 kcal/mol. You now set up another reaction in which you have doubled the amount of Lysozyme to 10 nM. What do you predict will be the DG for the new reaction? Explain your answer.
Answer: No change in dG.
Explanation:
G = Gibbs free energy
dG is a measure of spontaneity.
It is a quantitative measure of the favorability of a reaction.
It is affected by enthalpy and entropy.
dG = dH -TdS
dG is not dependent on enzyme concentration.
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You are studying an enzymatic reaction catalyzed by Lysozyme, an enzyme present in human mucous. Lysozyme...