Hyperphosphorylation of proteins by the Sik3 protein explains: a. why Dreamless mutants have reduced REM. b....
Hyperphosphorylation of proteins by the Sik3 protein explains:
a. why Dreamless mutants have reduced REM.
b. why Sleepy mutants are so sleepy.
c. why Dreamless mutants have increased REM.
d. why Sleepy mutants and sleep-deprived wild type mice are sleepy.
Homework Answers
Answer )b. why Sleepy mutants are so sleepy.
The Sleepy mutant allele of the Sik3 protein kinase gene markedly increases daily nonrapid-eye movement sleep (NREMS) amounts and sleep need. So single amino acid change or Phosphorylations produce a change in SiK3 and produce Hypersomnia Phenotype of Sleepy mutant mice .Such sleepy mutants are so Sleepy and have increased NREM type of sleep ( Non rapid eye movement ) .
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Hyperphosphorylation of proteins by the Sik3 protein
explains:
a. why Dreamless mutants have reduced
REM.
b....
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