What is happening to the plus and minus ends of kinetochore microtubules in mitosis prior to...
What is happening to the plus and minus ends of kinetochore microtubules in mitosis prior to anaphase (anaphase A) and in anaphase (anaphase A) [is there net growth or disassembly at these ends and times?]
Homework Answers
This occurs through the action of the kinetochore microtubles(illustrated in the inset).These microtubules shorten at their plus ends,while the kinetochores of the chromatids travel towards the minus ends;thereby,the sister chromatids remain attached to the shortening microtubules.
The seperation of sister chromatids during anaphase is the culmination of mitosis and one of the examples of cellular movement.it consists of two distinct processes:Anaphase the movement of chromosomes towards spindle poles via shortening of the connecting fibres,and anaphase B.
Anaphase consists of at least two distinct processe,traditionally referred to as anaphase A and anphase B. Anaphase A is the movement of chromosomes toward the spindle poles via shortening of the connecting fibers.
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What is happening to the plus and minus ends of kinetochore
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Isolated bundles of actin filaments from the acrosomal processes
of Limuluspolyphemus(horseshoe crab) sperm have readily
distinguishable plus ends (tapered) and minus ends
(blunt). Assembly at the ends of such bundles was used
to determine the mechanism of action of phalloidin, which has a
marked effect on actin assembly. When phalloidin is mixed with
actin in a molar ratio of at least 1:1, the growth rate increases
at both ends, as shown for minus ends in Fig.
16-11A. Because growth rate = kon[actin]...
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