Question

1. In the structure of the antibiotic Aztreonam illustrated below, how many nitrogen atoms have a sp2 hybridization state?

O=s=0 ŽI -NH

2. What is the number of oxygen atoms on which the negative charge will resonate by following relevant resonance structures? (0,1,2,3,4 or 5)

3. Identify the stereochemistry of each of these double bonds marked 1 and 2 in the structure below ((E) or (Z))

4. What is the absolute configuration of the following molecule? (R/S)

5. Determine the relationship between these different pairs of compounds (Constitutional isomer, Diastereoisomers, Enantiomers, same compounds)

6. What structure represents the Newman projection shown below?

7. What structure represents the Newman projection shown below?

8. Which structure corresponds to the chair configuration below?

9.What chair conformation does it correspond to the molecule below?

10. What is the most stable chair conformation of the 4-methoxy-1,2-dimethylcyclohexane structure given below?

Answer 1

1. There are 2 nitrogen atoms that have sp2 hybridization state. The nitrogen atom that do not attached to any of the hydrogen have sp2 hybridization here.