Ans) BPG is the short name of 2,3-bisphosphoglycerate. This compound is formed from 1,3-bisphosphoglycerate, which is an intermediate of glycolysis. When 1,3-BISPHOSPHOGLYCERATE accumulates in blood, it gets converted into BPG.
One molecule of BPG binds to tetramer hemoglobin in T form. It stabilizes, thereby, the deoxygenated form of hemoglobin. The increased concentration of BPG the affinity of hemoglobin for oxygen.
At high altitude, partial pressure of oxygen is low. So, body requires more oxygen to fulfill his needs. For this some adaptations are needed at high altitude. For example, respiratory rate increases and erythrocyte number increases. Also BPG facilitates the release of oxygen in tissues from hemoglobin by lowering the affinity of hemoglobin for oxygen in tissues.
Diagram is as follows :
Explain the role of BPG in Hb function. How is BPG involved with adaptation to high...
2) We discussed in class how the molecule 2,3-bisphosphoglycerate (BPG) is an inhibitor of hemoglobin (Hb). Answer the following questions about BPG and its regulation of oxygen binding: a) Would BPG have any effect on myoglobin’s ability to bind or release oxygen? If so, describe how BPG would affect myoglobin. If not, why? b) Based on the observation that BPG binds preferentially to partially deoxygenated Hb, briefly explain (1-2 sentences) where BPG is most likely to be most effective on...
BPG (bisphosphoglycerate) is involved in the adjustment of Oxygen delivery at high altitude. Briefly explain how this works.
2, High altitude pulmonary edema (and high altitude cerebral edema) are the major causes of death from altitude sickness, triggered by hypoxic conditions. a. Recall that alveolar ventilation and blood flow to pulmonary capillaries are matched to maximize diffusion of oxygen into the blood. when climbers eceed about 2500m of altitude they experience significantly low levels of atmospheric oxygen. How does this affect the state of contraction of their pulmonary arterioles? b. How would hypoxix conditions affect pressure in the...
Explain how the Geometric structure of a Biological molecule plays a role in its function.
DIAGRAM and BRIEFLY explain how energy from high energy electron carriers is converted to ATP during respiration in mitochondria and aerobic bacteria. Label each process involved in energy conversions, and label two of the proteins involved in the final steps of making ATP. (compare this to ATP production during Photosynthesis) [hint: discuss electrons, gradients, and phosphates, and the proper terms for the pathways involved.]
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The following contingency table illustrates how a survey of public employees responded to questions regarding income and job satisfaction. Determine the probability of the following events and explain its meaning. (3 pts each) Table 14.14 Relationship between Income and job Satisfaction Iacome Job Satisfaction Low 100 60 40 Medium 30 80 40 10 Medium Hi 50 a. b. c. d. e. Medium job satisfaction At least medium income High job satisfaction or high income Lowjob satisfaction and medium income Low...