Question
The next gel is from a crime scene (CS). There are four suspects (A, B, C, and D). DNA samples and four suspects were obtained from the crime scene. You can predict which of these is guilty of the crime. Explain your answer and why the other suspects are not to blame.

A B D BXP007 alleles Wave 21||||||| AL: Allele ladder CS: Crime Scene A: Suspect A B: Suspect B C: Suspect D: Suspect D 5-2 7
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Answer #1

Answer: Suspect B may be the culprit
Explanation:
DNA fingerprinting is a diagnostic method to determine the source of DNA based on DNA polymorphism.
Individuals contain 99.9% identical genomic sequence. However, the remaining 0.1% of the genome (3 X 10^8 bp) exhibits polymorphism.
This polymorphism can be SNPs or in-dels or inversions or duplications.

The crime scene sample is taken as a reference to identify its origin. From the given image, it is clear that suspect B exhibits an identical banding pattern to the crime scene sample.
See the image

AL CS A B C D 5-2 7-4 5-2 7-2 10-3 genotype

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