#1.
What is calcineurin?
Compare its method of activation and signaling of downstream
targets with that of the insulin receptor in table format.
What is a
disease associated with it and a drug that can be
used to block its activity.
#2.
What is the Philadelphia chromosome and the disease associated with
it? Explain the signaling mechanism of the
2 genes
when fused. What
is TASIGNA and how can it
be used as a specific
pharmaceutical for treatment?
#3. What are SERMs? Explain their target and mode of action. What concerns are there in the use of SERMs.What are SERDs and how do they compare to SERMs?
#1. What is calcineurin? Compare its method of activation and signaling of downstream targets with that...
related to insulin signaling This is related to insulir cell signaling 1) Describe the steps between the binding of an insulin molecule at the surface and the activation of the effector PI3K of the target cell 2) How does the action of the insulin receptor differ from other ligands that act by means of receptor tyrosine kinases? 3) What is the relationship between type 2 diabetes and insulin production? How is it that a drug that increases insulin sensitivity might...
Final Exam Review 1. What type of insulin is used in emergency situation. 1. What is the purpose of sedatives 2. Drugs used for inflammation. What is the purpose of hypnotics. 3. 4. What is the level of abuse of schedule IV drug. 5. What is trough. 6. What is peak. 7. Before mixing two medications in a syringe, what should the nurse determine first. 8. History of which disease has the most effect on metabolism. What is the order...
explain 1 or 2 molecular details in how epigenetics may allow melanoma cells to outsmart BRAF inhibitors **This is for a genetics course Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
Chapter 57 1.Explain the glycosylated hemoglobin (hemoglobin A1c), what it reflects (in terms of blood chemistry), and why it is an important adjunct to (total) blood glucose levels in monitoring the response of diabetes to therapy. 2. Be able to discuss diabetic ketoacidiosis 3. Identify the main groups of oral antidiabetic drugs (and a prototype in each). Compare and contrast their main mechanisms of action, their main adverse responses, and drug–drug interactions 4. State three classic signs or symptoms of diabetes and identify...
1. What are the 2 main ways that hormones can interact with their target cells? Which chemical classes of hormones use each of the different mechanisms? Give an example of each type of hormone. 2. Hormones may interact with each other in one of 3 ways to alter body function. Describe each type of interaction and give an example of hormones involved in each one. 3. How do circulating hormones differ from paracrines & autocrines? 4. How does a portal...
Please answer all the questions (1-6) Thank you. I’ll be sure to leave you a like :) check Your Understanding 5. How does the mutated CFTR protein contribute to What is the difference between genetic engineering and cloning a. Genetic engineering is governed by an international cystic fibrosis? a. The mutation prevents the channel protein from moving chloride across the membrane, resulting in a thick, sticky mucus ethics committee. Cloning does not have any formal ethics oversight. b. The mutation...
can someone answer questios 1-13? nstructure.com/courses/11471/quizzes/231523/take Question 1 0.5 pts A cell spends most of its life in what stage of the cell cycle? O Interphase O Prophase O Metaphase O Telophase O Cytokinesis D Question 2 0.5 pts TRUE or FALSE: Gap intervals are periods of inactivity. O True O False | Question 3 4 pts Briefly explain why checkpoints exist, when they occur, and what they are responsible for HTML Editor ucture.com/courses/11471/quizzes/231523/take Question 3 4 pt Briefly explain...
1. According to the paper, what does lactate dehydrogenase (LDH) do and what does it allow to happen within the myofiber? (5 points) 2. According to the paper, what is the major disadvantage of relying on glycolysis during high-intensity exercise? (5 points) 3. Using Figure 1 in the paper, briefly describe the different sources of ATP production at 50% versus 90% AND explain whether you believe this depiction of ATP production applies to a Type IIX myofiber in a human....
does anyone know what High and low group means in this context? i really do not understand this article so anyone that does please explain it to me and what the hugh and low group mean in the figures. Received: 21 November 2018 Revised: 27 February 2019 Accepted: 6 March 2019 DOE: 10.1002p28546 ORIGINAL RESEARCnes-highdearee of intra modole connecHvity WILEYa Phypliology ARTICLE Four novel biomarkers for bladder cancer identified by weighted gene coexpression network analysis Zi-Xin Guo | Xiao-Ping Liu...
Please read the article bellow and discuss the shift in the company's approach to genetic analysis. Please also discuss what you think about personal genomic companies' approaches to research. Feel free to compare 23andMe's polices on research with another company's. Did you think the FDA was right in prohibiting 23andMe from providing health information? These are some sample talking points to get you thinking about the ethics of genetic research in the context of Big Data. You don't have to...