Summery: the above Reaction
which having simple synthesis by using an Aromatic Subsitution
reaction. Only we have to remember the Acitivating and
Deacitivating group on aromatic Ring. Also use some reagent to
followed the synthesis
C. Synthesis Strategies C1. How will you synthesize the following compounds starting from Benzene? нозсуві ON...
Synthesis 18.63) Synthesize each compound from benzene and any other organic or inorganic reagents. Br- CICINO, OYNH2 COOH O2N. -C NH2 НО ОН SO3H HOOC (PABA) sunscreen component
Starting with benzene, how would you synthesize the following
products? You can use any chemical you can find from chapter 7- 13,
or 16-18 to help you in your synthesis. (15 pts, 5 points
each)
3. Starting with benzene, how would you synthesize the following products? You can use any chemical you can find from chapter 7-13, or 16-18 to help you in your synthesis. (15 pts, 5 points each) OH o-bo
5. Provide a synthesis of the following compounds from the given starting material. (Complete any two for 8 pts each-if you do a third, it w'll be treated as extra credit.) NO2 From benzene Br From benzene as the source of at least one aromatic ring H2N Extra Credit: Explain why p-methoxybenzyl bromide (A) is more reactive than p-nitrobenzyl bromide (B). Be thorough. (6 pts) 6. O2N
synthesize the following compounds from benzene.
balance reactions.
SOH HO, SO3H
sbow how you woukd synthesize each of the following compounds from
benzene
(a) Show how you would synthesize each of the following compounds from benzene. Br (b) (c) (d) NHA Br. Br. (e) HN NH2
Starting with benzene as your only source of aromatic compounds, how would you synthesize the following substances? Assume that you can separate ortho and para isomers if necessary. p-Chlorotoluene m-Bromonitrobenzene o-Bromobenzenesulfonic acid m-Chlorobenzenesulfonic acid Starting with either benzene, phenol, or toluene, how would you synthesize the following substances? Assume that ortho and para isomers can be separated 2-Bromo-4-methylphenol 1,3,5-Trinitrobenzene 2,4,6-Tribromoaniline 2-Chloro-4-nitrotoluene
20. Starting from benzene or anisole and any other reagent of your choice, design a synthesis for each of the following compounds. (18 pts) 21. Predict the products from the Birch reductions shown below. (3 pts) Na GLO Bonus: (6 pts) Provide a synthesis for the target molecule using benzene. COH COH TM
Starting with benzene and using any other neccessary reagents of
your choice, design a synthesis for each of the following:
OMe COOH Br Br NO NO (b) COOH NH Cl Cl NO2 COOH NO2 Cl NO Cl Br OEt NO2 Cl (h) C (g) NO2 Br O2N
5. How would you synthesize the following compounds A-D starting from toluene? но toluene B C D
5. How would you synthesize the following compounds A-D starting from toluene? но toluene B C D
Starting with benzene prepare each of the fol1wing: CHз SO3H SO3H Br Br NO2 COOH соон CHЗ C2HS c1 NO2 NO2 NO2 CHЗ Соон NO2 NO2 NO2 СОон