23. Please answer the questions regarding to the following reactions. (12 pts) (a) CI + T...
Tulung ate n illud aludke place in a single step. In the Sn2 reaction, the nucleophile attacks the a-carbon from the backside and displaces the leaving group with an inversion of configuration occurring at the carbon. In the E2 elimination reaction, strong base removes an acidic hydrogen from the B-carbon and an alkene is formed as the leaving group is expelled from the a-carbon. This elimination follows Zaitsey's rule whereby the more substituted alkene is generally formed. In E2 elimination,...
4. Predict the products of the following reactions & indicate whether they are most likely to go through an SN2, SN1, E1, or E2 mechanism. NaCN DMSO NaOH CH3OH heat Only one product is formed in the following E2 elimination reaction. Draw an arrow-pushing mechanism for the reaction and provide the correct product structure. Include a 3-D drawing (chair conformation) displaying proper stereochemistry of the transition state to explain formation of only the major product. CH3 •Br NaOCH3 ~"'CHS
Short Answer Section (43 pts) - showing work helps! Substitution us. Elimination (12 pts). Predict all major product(s) of each of the following reactions and indicate the predominant mechanistic pathways (Snl. S. 12). Remember to consider rearrangements mechanisms? mechanisms? for this reaction, circle the major product mechanism(s) for this reviction, circle the major product mechanism(s)? Mechanism +1 (10 pts). Draw a stepwise mechanism to account for the following transformation
Chemistry 12A Substitution and Elimination Reactions 1. Provide complete curved-arrow mechanisms for the following transformations, Label the overall mechanism as: E1, E2, S,2, or Sy1 and explain in 1 sentence WHY that mechanism is favored. Br OH OH Br кови Hао Br "ОН conc. H2SO4 "Он
Short Answer Section (43 pts) – showing work helps! Substitution vs. Elimination (12 pts). Predict all major product(s) of each of the following reactions and indicate the predominant mechanistic pathways (Sn1, Sn2, E1, E2). Remember to consider rearrangements. Mechanism #1 (10 pts). Draw a stepwise mechanism to account for the following transformation. Br mechanism(s)? NaOH Cl mechanism(s)? NaOEt OTs for this reaction, circle the major product mechanism(s)? O K Cl for this reaction, circle the major product mechanism(s)? NaOCH3 H2O...
Predict the Major product(s) for the following reactions and draw their corresponding arrow-pushing mechanisms. If there is no reaction write NR. (21 points total) detailed Show the correct stereochemistry when needed KOH THF substitution Cl Mechanism: MeOH substitution Mechanism: CI t-BuOK, DMF heat elimination Mechanism:
Please, make the answer clear and reable. BrEtOH a OEt Hace H2C Alkyl halides undergo nucleophilic substitution and elimination reactions. When the kinetics of the reaction are measured, if the rate of the reaction is found to be dependent only upon the concentration of the alkyl halide the reaction is first order. The substitution reaction is thus termed ction is termed E1. These reactions are unimolecular and occur in two steps. The first step is rate-limiting and involves the loss...
o. Reactions. Please complete the following reaction schemes with the appropriate alkyl halide, reagent os NaOH Br NaCN SN27 elimination product(s) substitution product(s) SN1 кон elimination product(s) circle the major product substitution productis) SN1 t-butoxide NaOMe SN2? elimination product(s) circle the major product substitution product(s) | SNI NaF SN2? elimination product(s) substitution product(s) NaOH H2O E2] Br SN2? major elimination product depict correct stereochem (hint: antiperiplanar) substitution product(s) Br SN1 or SN2? H20 H20 all elimination product(s) watch for rearrangements...
help please im so lost...as much detail with explainations for the mechanisms 1. For the reactions below: (l) draw all elimination products that would form under the stated conditions, (2) circle the major products). (3) determine how (El or E2) and (4) explain your reasoning (45 p) CH OH 2. Provide a mechanism which explains the following conversion (pt) xriy For the reactions below: (1) draw all products that could form under the stated conditions, (2) determine how they formed...
Thank you so much! (2 pts) Draw the major elimination products and Identify the mechanism responsible (E1 or E2). If both E and Z isomers form, only draw the E alkene. If only one isomer forms, label the alkene "E,""Z," or neither 1. NaOCH3 а. Br НОСHЗ b. НОСНЗ C. CI NaOCH3 d. (6 pts) Draw the substitution and/or elimination product(s) for the following reactions and identify 2. the mechanism responsible (SN1, SN2, E1, or E2) for each product drawn....