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Complete the table below. [6] mRNA Amino Acid Mutation Effect Wild-type 5-GAA-3 Glu N/A Wild-type Mutant 1 DNA 3-CTT-5 5-GAA-

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Answer #1
DNA mRNA amino acid mutation effect
wild type

3'CTT5'

5'GAA3'

5'GAA3' glu N/A wild type
mutant 1

3'CAT5'

5'GTA3'

5' GUA3' val subsitution (transversion ) mutant
mutant 2

3'CTC5'

5'GAG3'

5'GAG3' glu subsitution (transition ) mutant
mutant 3

3'ATT5'

5'TAA3'

5'UAA3' stop codon subsitution (transversion ) mutant

subsitution mutation is of two types:

transversion : when purine is replaced by pyrimidine or pyrimidine is replaced by purine

transition : when purine is replaced by purine or pyrimidine is replaced by pyrimidine .

purines : A,G

pyrimidine : C,T

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