Question

For a large population, plot q (frequency of the disfavored allele) against time for the Homozygous Near-Lethal (near-lethal recessive), Homozygote and Heterozygote Disadvantage. Repeat this graph for the Heterozygote Superiority case. Thoroughly discuss and explain the differences indicated by your graphs.

Answer 1

Homozygous allele disadvantage:-

• The allele can be either lethal or non lethal
• Can express the hidden characters.
• No variants can be created
• No new populaton can be made.
• Sometimes less resistance compared to heterozygous allele.

Heterozygous allele disadvantage :-

• Some of the heterozygous allele is sterile
• can't be used to produce pureline, which is more important for breeding purpose.
• It have only low fitness.
  Homozygous Near Lethal allele 0.6 genotype frequency 0.2 0.2 0.4 0.6 0.8 1 allele frequency p Heterozygous Superority allele 0.8+ genotype frequency 0.6 0.4 0.2 1 0.2 0.4 0.6 0.8 allele frequency (q)
  

Summary of graph:

• frequency of heterozygote is highest at p = q = 1/2
• During selection homozygous is more referable than heterozygous