Question

Genotype A1A1A1A2 A2A2 Number before selection 150 300 150 Number after selection 120 225 105

Find the calculations for the data of this population?

a) Calculate the relative fitness for each of the three genotypes?

b) What is the mean fitness of this population, and how do you expect it to change in response to selection?

c) Based on the calculations in a), calculate the values of h and s. What type of selection has occured?

d) If the surviving individuals mate at random, what will be the genotype frequencies in the next generation ( i.e. assuming no other evolutionary forces intervene)?

e) Calculate the change in the frequency of allele A2 as a result of the frost.

f) What are the assumptions of the calculation in e), and what is the biological interpretation of this result?



*This is Population Genetics*

• Construct the following table AA2 A,Az 2pq Genotype AA Frequency of zygotes Relauve fitness Product Frequency of adults pw/

At what condition, the population will reach equilibrium Ap=0)? • The allele frequency will no longer change • Solve the foll



W2> Wand > W22 W2win and 2 <w22 • When the heterozygote has the highest fitness or the lowest fitness, the population will re

Heterozygosity superiority • Heterozygote has the highest fitness. • W.2>W11 and 12>W22 . Consequence: Genetic variability pr

Overdominance model (p164) • W+s = 1 • Often scale the fitness to the heterozygote •S,>, S,>0, select against A1A1 and A2A2 (



Natural Section Equations outside of Hardy-Weinberg.

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Answer #1

In population Genetics;

For a population genetic equilibrium:

P + Q =1.0 (the sum of frequency of both allele is 100%).

In population genetic studies,the Hardy-weinberg equation can be used to measure whether the observed genotype frequencies in a population differ from the frequency is predicted by the equation..

**a))The relative fitness for each of the genotypes are;

Before selection:

A1A1 A1A2   A2A2

150/3=50 300/3=100 150/3=50

After selection:

A1A1 A1A2 A2A2

120/3=40 225/3=75 105/3=35

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