Question

Value: 15 According to the information provided in the weblinks above, which of the following mutations would have been negatively selected for in populations of andeans living at low altitudes? ("Upregulation" means more production of the gene's product.) a. a gene that codes for the starch digestion enzyme MGAM b. a mutation in the gene which codes for an immune receptor (CD83) and results in upregulation (more production of the receptor) c. a mutation in the JAK2 gene which upregulates RBC production d. A mutation in the DST gene which results in upregulation. Value: 15 Does having mutations in noncoding regions of a genome exert any type of selection (negative or positive)? a. No, only mutation in coding regions of the gene can exert any type of selection pressure. b. Yes, if they happen to be in regulatory regions of the genome. c. Yes, if they happen only in high altitude living populations. d. No, selection can only be positive so the mutations needs to result in a protein with improved function.

Answer 1

Part 1st doesn't have the reference mentioned in the question.

The answer of part 2nd will be (B) as mutations in the non-coding regions can exert both types of selections, i.e negative as well as positive.