Homework Answers
3 a) Acetylation helps in DNA transcription and repairs damaged genetic material. Phosphorylation helps in the regulation of activity of enzymes. And glycosylation helps in promoting protein folding, stability as well as regulatory functions. That's y these are necessary cellular modifications.
b) physiology of muscle contraction involves several interactions. Myosin filament acts as molecular motors and by binding to actin enable filament sliding.
Furthermore members of skeletal muscle lipid droplet Assosciated proteins family assosciate with other proteins as activator of adipose triglyceride lipase and it's Coactivator comparative gene identification 58,to regulate lipolysis in skeletal muscles.
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Q3. Answer BOTH parts. (a) Discuss why acetylation, phosphorylation and glycosylation of proteins are necessary cellular...
Why are proteins heat denatured prior to analysis in SDS-PAGE? Select all answers that apply. Denaturation...
Why are proteins heat denatured prior to analysis in SDS-PAGE? Select all answers that apply. Denaturation of the protein is necessary so that proteins run proportionally to their size, based on the interaction of SDS with the unfolded protein. Heat is used to hydrolyze the peptide bonds of the protein. The heat step allows the proteins to unfold, enabling the protein chain to be coated with SDS molecules. Heat is used to hydrolyze disulfide bonds. QUESTION 2 1.5 points Saved...
Scientists want to design fluorescent marker proteins for different cellular compartments using the Green Fluorescent Protein...
Scientists want to design fluorescent marker proteins for different cellular compartments using the Green Fluorescent Protein (GFP). This means that the GFP will be targeted and glow at the organelle of interest and they can use these to mark different organelles during fluorescence microscopy. To make these marker proteins, they take the sequence of GFP and add the desired sorting signal. A. GFP on its own is an excellent protein to use as an organelle marker protein because it is...
General Biology Chapter 6 Cellular Respiration Exercise For the Following questions, answer each thoroughly and sketch...
General Biology Chapter 6 Cellular Respiration Exercise For the Following questions, answer each thoroughly and sketch the parts of the Cell and/or Mitochondrion to illustrate your answer. 1. Triglycerides can be broken down by hydrolysis reactions to glycerol and fatty acid chains in the digestive tract. Glycerol is easily converted to 1 phosphoglyceraldehyde also known as PGAL Using your knowledge about how aerobic cellular respiration functions, explain how from this original glycerol molecule how many ATP's are formed in this...
. Gleevec (Imatinib) inhibits protein kinase BCR-ABL, which is constitutively active in patients with Chronic Myelogenous...
. Gleevec (Imatinib) inhibits protein kinase BCR-ABL, which is
constitutively active in patients with Chronic Myelogenous Leukemia
(CML). The structure of Gleevec is shown below:
a) Based on our discussion in lecture and the structure above,
explain how the “lead” compound structure for Gleevec was designed
and how it led to the development a compound that could bind ABL
with higher affinity than ATP.
b) Using a broad kinase inhibition assay, you discover that
Gleevec inhibits another tyrosine kinase called...
Not sure how to answer these immunology questions! Help! 1) An otherwise healthy person is involved...
Not sure how to answer these immunology questions! Help! 1) An otherwise healthy person is involved in an accident that requires kidney transplantation within a week. As the attending immunologist you are aware of three family members (no identical twins) that are willing to donate a kidney. What would you do to prepare the patient to minimize rejection?1) Detail three tests you would use to determine your ultimate donor tissue. Outline the rational that you would use to choice your...
Please answer all the parts of the question clearly and fully! Thank you! Numerical Answers: (b)...
Please answer all the parts of the question clearly and fully!
Thank you!
Numerical Answers:
(b) (0.0 A, 24 V), (approximately 1.6 A, 0.32 V)
(c) 38.4 W, 0.5 W
(e) 0.26 W + 1.5 mW
SECTION B: Attempt any Two) questions 150 marks total! Q3 A MOSFET is used as a low-side switch to control a 15 2 resistive load from a 24 supply. The MOSFET has RDSan VDC 0.2 ? and ton-tof-40 ns. (a) Draw a suitable circuit....
please answer all that you can 1. You have genetically engineered green fluorescent protein (GFP) containing...
please answer all that you can 1. You have genetically engineered green fluorescent protein (GFP) containing a KDEL sequence (GFP-KDEL). When GFP-KDEL is expressed in normal human fibroblasts and examined using fluorescence microscopy, the fluorescence appears diffuse across the cytoplasm. How would you explain this observations given that KDEL is supposed to be an ER-specific sorting sequence? A. This engineered GFP would not have a hydrophobic signal sequence to get it into the RER in the first place. B. The...
Q1. Mendel used Garden Peas varieties (Pisum sativum) in his genetic study. Describe the characteristics of...
Q1. Mendel used Garden Peas varieties (Pisum sativum) in his genetic study. Describe the characteristics of this species as model organism of genetic study. What two most important factors contributed in discovering the law of segregation and law of independent assortments? Explain! (10 points) Q2. How do both dominant and recessive cellular functions appear in the human female adult body? Describe the molecular mechanism for the outcome of the two alternate cellular proteins in different tissues. (10 Points) Q3. A...
Just try to answer the math parts of the questions, thanks. Medical Study Problem: Make sure...
Just try to answer the math parts of the questions,
thanks.
Medical Study Problem: Make sure that all members of your team
understand this important application of traditional statistics. A
medical study compared the success rates of two treatments for
kidney stones. Each treatment was applied to two groups of people –
one group in which each subject had a small stone and one group in
which each subject had a large stone. Based on various numbers of
patients in...
YOU MUST ANSWER THE FOLLOWING QUESTIONS ON YOUR OWN PRIOR TO CLASS REVIEW! 1. Label the...
YOU MUST ANSWER THE FOLLOWING QUESTIONS ON YOUR OWN PRIOR TO CLASS REVIEW! 1. Label the path of electrons through the light reactions of photosynthesis using the illustration below. A. Include PSII and PSI and label all the complexes involved i. Which complex pushes H* across the membrane? ii. Where do these electrons end up? iii. What is the purpose of splitting H2O? iv. Where do the light reactions take place? 2H2D Ot ENR NAOD ADP photolyetemi photosyetemi wlochtone be-...
Why are proteins heat denatured prior to analysis in SDS-PAGE? Select all answers that apply. Denaturation of the protein is necessary so that proteins run proportionally to their size, based on the interaction of SDS with the unfolded protein. Heat is used to hydrolyze the peptide bonds of the protein. The heat step allows the proteins to unfold, enabling the protein chain to be coated with SDS molecules. Heat is used to hydrolyze disulfide bonds. QUESTION 2 1.5 points Saved...
Scientists want to design fluorescent marker proteins for different cellular compartments using the Green Fluorescent Protein (GFP). This means that the GFP will be targeted and glow at the organelle of interest and they can use these to mark different organelles during fluorescence microscopy. To make these marker proteins, they take the sequence of GFP and add the desired sorting signal. A. GFP on its own is an excellent protein to use as an organelle marker protein because it is...
General Biology Chapter 6 Cellular Respiration Exercise For the Following questions, answer each thoroughly and sketch the parts of the Cell and/or Mitochondrion to illustrate your answer. 1. Triglycerides can be broken down by hydrolysis reactions to glycerol and fatty acid chains in the digestive tract. Glycerol is easily converted to 1 phosphoglyceraldehyde also known as PGAL Using your knowledge about how aerobic cellular respiration functions, explain how from this original glycerol molecule how many ATP's are formed in this...
. Gleevec (Imatinib) inhibits protein kinase BCR-ABL, which is
constitutively active in patients with Chronic Myelogenous Leukemia
(CML). The structure of Gleevec is shown below:
a) Based on our discussion in lecture and the structure above,
explain how the “lead” compound structure for Gleevec was designed
and how it led to the development a compound that could bind ABL
with higher affinity than ATP.
b) Using a broad kinase inhibition assay, you discover that
Gleevec inhibits another tyrosine kinase called...
Please answer all the parts of the question clearly and fully!
Thank you!
Numerical Answers:
(b) (0.0 A, 24 V), (approximately 1.6 A, 0.32 V)
(c) 38.4 W, 0.5 W
(e) 0.26 W + 1.5 mW
SECTION B: Attempt any Two) questions 150 marks total! Q3 A MOSFET is used as a low-side switch to control a 15 2 resistive load from a 24 supply. The MOSFET has RDSan VDC 0.2 ? and ton-tof-40 ns. (a) Draw a suitable circuit....
Q1. Mendel used Garden Peas varieties (Pisum sativum) in his genetic study. Describe the characteristics of this species as model organism of genetic study. What two most important factors contributed in discovering the law of segregation and law of independent assortments? Explain! (10 points) Q2. How do both dominant and recessive cellular functions appear in the human female adult body? Describe the molecular mechanism for the outcome of the two alternate cellular proteins in different tissues. (10 Points) Q3. A...
Just try to answer the math parts of the questions,
thanks.
Medical Study Problem: Make sure that all members of your team
understand this important application of traditional statistics. A
medical study compared the success rates of two treatments for
kidney stones. Each treatment was applied to two groups of people –
one group in which each subject had a small stone and one group in
which each subject had a large stone. Based on various numbers of
patients in...
YOU MUST ANSWER THE FOLLOWING QUESTIONS ON YOUR OWN PRIOR TO CLASS REVIEW! 1. Label the path of electrons through the light reactions of photosynthesis using the illustration below. A. Include PSII and PSI and label all the complexes involved i. Which complex pushes H* across the membrane? ii. Where do these electrons end up? iii. What is the purpose of splitting H2O? iv. Where do the light reactions take place? 2H2D Ot ENR NAOD ADP photolyetemi photosyetemi wlochtone be-...
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