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16 If other conditions were to remain constant, which one of the following changes would explain a reduced rate of activity i
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Answer: Option A ) an increase in the concentration of the end products.

Reason:

The end product of the enzyme-catalysed may act as a repressor or inhibitor, which reduces the rate of enzyme activity.

Although, the increase of temperature and pH may reduce the enzyme activity, and increase in these parameters towards the optimum range as mentioned, would not cause this effect.

Similarly, the increase of substrate and enzyme concentration leads to a rise in enzyme activity, uptil a certain point, and beyond this point it does not cause any change in the activity.  

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