Question

1. Which of the following statements are true about adipose tissue? a. Brown adipose tissue is responsible for storage of energy b. Brown adipose tissue is responsible for producing heat (thermogenesis) c. White adipose tissue is responsible for producing heat (thermogenesis) d. White adipocytes have more mitochondria than brown adipocytes. e. Brown adipocytes have a large lipid droplet 2. Which protein is known as the "master regulator of adipocyte differentiation"? a. PPAR b. SNP c. STZ d. P53 e. Ras 3. Which of the following statements about fat soluble hormones is true? a. They typically dissolve in water b. They are typically formed from cholesterol c. They cannot freely pass through the cellular membrane d. They bind to receptors found on the cell surface e. They are typically made from amino acids 4. Which of the following statements is FALSE regarding Diethylstilbestrol (DES)? a. Synthetic non-steroid estrogen b. Binds to estrogen receptor a much stronger than estradiol (3-5 fold) c. Leads to miscarriage and tumors in the fetus d. Binds to estrogen receptor a much stronger than estradiol e. Induces aromatase, which converts androgen into estrogen

Answer 1

1. b. Brown adipose tissue is responsible for producing heat (thermogenesis) is a true statement.

Brown fats are found in new born babies. Brown adipose tissue has a protein thermogenin that causes the uncoupling of protons and restrict its movement along mitochondrial gradient consequently synthesis of ATPand is stopped, and this energy is dissipated in the form of heat.

2. a. PPAR is true statement.

PPAR is known as the master regulator of adipocyte differentiation because peroxisome proliferator-activated receptor (PPAR) is a transcription factor that control the differentiation of preadipocytes into adipocytes.

3. b. They are typically formed from cholesterol.

Fat soluble hormones not dissolvd in water. They can easily pass from cellular membrane because it is lipid soluble. They can bind with receptors inside and outsie of the cell whereas water soluble hormones bind only on surface receptors. They are not made up of amino acid

4. e. Induces aromtase, which converts androgen into estrogen is a false statement.

Except e all statements are true..