help pleaseHomework Answers
Answer =
The mutations would lead to a change in the reading frame in translation is
Deletion of two cytosines.
Explanation - The mutations would lead to a change in the reading frame in translation is called as frameshift mutation.
only frameshift muattaion is the type of mutation that causes change in reading frame.
frameshift mutation arises when there is addition or removal of one or more nucleotide in DNA sequence.
But the condition is that the number of nucleotides that are added or removed are not in a multiple of three.
there will be no shift in the codon reading frame.
the result of addition or removal of three nucleotides is that , there will either be one extra or one missing amino acid in the final protein.
therefore insertion of two cytosines is correct option, it would lead to the change in the reading frame in translation.
INCORRECT OPTIONS =
Insertion of CTA codon - it leads to extra one amino acid in reading frame.
insertion of six adenines- it leads to extra two amino acid in reading frame.
because there will be no change in shift in reading frame.
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