Which of the following mutations would be most likely to have a harmful effect on an...
Which of the following mutations would be most likely to have
a
harmful effect on an organism?
(A) a deletion of three nucleotides near the middle
of a gene
(B) a single nucleotide deletion in the middle of an intron
(C) a single nucleotide deletion near the end of the coding
sequence
(D) a single nucleotide insertion downstream of, and close
to,
the start of the coding sequence
In this problem, why (c) cannot be the answer??
Single nucleotide deletion occurs frameshift mutation.
I understand that the answer is d, but please let me know why c is not the answer.
Homework Answers
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Which of the following mutations would be most likely to have
a
harmful effect on an...
Which of the following mutations would cause the most harmful effect: 1) a single base insertion...
Which of the following mutations would cause the most harmful effect: 1) a single base insertion near the beginning of the coding sequence or 2) a three base deletion towards the end of the coding sequence.
1. Which of the following mutations is the most likely to be neutral? A) A nonsense...
1. Which of the following mutations is the most likely to be neutral? A) A nonsense mutation in exon 5 of a gene with 39 exons. B) A splice site mutation in intron 3 of a gene with 8 introns and 9 exons. C) A single nucleotide insertion in exon 7 of a gene with 18 exons. D) A thee nucleotide deletion in exon 1 of a gene with 7 exons.
Which mutation is most likely to have a severe impact on the phenotype of an organism...
Which mutation is most likely to have a severe impact on the phenotype of an organism if it occurs within the first several bases of a gene coding region? A) a frameshift mutation of three nucleotides B) a missense mutation affecting one nucleotide C) a missense mutation affecting three nucleotides D) a silent mutation affecting one nucleotide E) a frameshift mutation of one nucleotide
1) Using the bacterial DNA sequence that the instructor gave you:
1) Using the bacterial DNA sequence that the instructor gave you:a. Identify and underline the promoter region and the start codon.b. Identify the coding and template strandc. Transcribe the coding sequenced. Translate the mRNA sequence8) Which of the following mutational changes would you predict to be the most deleterious to gene function? Explain your answers.a. Insertion of a single nucleotide near the end of the coding sequence.b. Removal of a single nucleotide near the beginning of the coding sequence.c. Deletion...
1) Which of the following mutations could result in a frameshift? A) a base insertion B)...
1) Which of the following mutations could result in a frameshift? A) a base insertion B) a base deletion C) a base substitution D) either A or B E) A, B, and C 2) Which of the following point mutations would be most likely to result in a non-functioning protein? A) a single base substitution in an intron B) a single base deletion near the end of the coding sequence C) a single base deletion in the codon following the...
The following sequence represents triplets on DNA: TAC CAG ATA CAC TCC CCT GCG ACT a....
The following sequence represents triplets on DNA: TAC CAG ATA CAC TCC CCT GCG ACT a. Give the mRNA codons and tRNA anticodons th b. c. Induce an insertion of one nucleotide in the original sequence? Do the same for 2 nucleotides then 3 d. Substitute one nucleotide in the original sequence. How does each insertion affect the amino acid at correspond with this sequence, and then give the sequence of amino acids in the polypeptide. induce a deletion in...
6. Which of the following mutations would most likely have the severest consequences: Explain your reasoning....
6. Which of the following mutations would most likely have the severest consequences: Explain your reasoning. a. A change in amino acid recognition of an aminoacyl-tRNA synthetase b. A frame shift mutation at the end of the coding sequence of a gene A mutation at a splice junction C.
Which of the following mutations is most likely to result in a non-functional protein? a) a...
Which of the following mutations is most likely to result in a non-functional protein? a) a single-nucleotide substitution in a promoter b) an insertion in an intron c) a frameshift mutation d) a missense mutation You have conducted an Ames test on a given compound to determine whether it is a mutagen. Which of the following would be classified as a positive result on the Ames test? a) originally His+ strain grows on minimal medium with histidine. b) originally His+...
Which of the following statements regarding gene mutations is NOT true? Conditional mutations have different phenotypic...
Which of the following statements regarding gene mutations is NOT true? Conditional mutations have different phenotypic effects under different conditions and can be used to study the function of essential genes. Silent mutations cannot have any phenotypic effect on an organism. Frameshift mutations often result in a truncated protein product, similar to a nonsense mutation. Dominant mutations have a phenotypic effect despite the presence of one functional wild type allele.
a) Its time to refresh your memory on the different types of DNA mutations. Define the...
a) Its time to refresh your memory on the different types of DNA mutations. Define the following: • point mutation, substitution, transversion, transition, point deletion, point insertion, frameshift mutation b) Define “gene regulation” and describe why this is an important process for all cells? c) Define operon and describe the major components that exist in an operon. Why are operons most common in prokaryotes but not in eukaryotes? d) Differentiate between “inducible operon” and “repressible operon”.
1. Which of the following mutations is the most likely to be neutral? A) A nonsense mutation in exon 5 of a gene with 39 exons. B) A splice site mutation in intron 3 of a gene with 8 introns and 9 exons. C) A single nucleotide insertion in exon 7 of a gene with 18 exons. D) A thee nucleotide deletion in exon 1 of a gene with 7 exons.
1) Using the bacterial DNA sequence that the instructor gave you:a. Identify and underline the promoter region and the start codon.b. Identify the coding and template strandc. Transcribe the coding sequenced. Translate the mRNA sequence8) Which of the following mutational changes would you predict to be the most deleterious to gene function? Explain your answers.a. Insertion of a single nucleotide near the end of the coding sequence.b. Removal of a single nucleotide near the beginning of the coding sequence.c. Deletion...
The following sequence represents triplets on DNA: TAC CAG ATA CAC TCC CCT GCG ACT a. Give the mRNA codons and tRNA anticodons th b. c. Induce an insertion of one nucleotide in the original sequence? Do the same for 2 nucleotides then 3 d. Substitute one nucleotide in the original sequence. How does each insertion affect the amino acid at correspond with this sequence, and then give the sequence of amino acids in the polypeptide. induce a deletion in...
6. Which of the following mutations would most likely have the severest consequences: Explain your reasoning. a. A change in amino acid recognition of an aminoacyl-tRNA synthetase b. A frame shift mutation at the end of the coding sequence of a gene A mutation at a splice junction C.
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