Which mutation is most likely to have a severe impact on the phenotype of an organism...
Which mutation is most likely to have a severe impact on the phenotype of an organism if it occurs within the first several bases of a gene coding region?
A) a frameshift mutation of three nucleotides
B) a missense mutation affecting one nucleotide
C) a missense mutation affecting three nucleotides
D) a silent mutation affecting one nucleotide
E) a frameshift mutation of one nucleotide
Homework Answers
Ans- E is correct. A frameshift mutation of one nucleotide likely to have a severe impact on the phenotype of an organism. Because frameshift mutation of one nucleotide cause change in more than one amino acids in a protein sequence. Frameshift mutation is a mutation in which addition or deletion of base pairs in a DNA resulting in the translation of the genetic code in an unnatural reading frame.
A frameshift mutation of three nucleotides only change one amino acid in a protein sequence.
Missense mutation and silent mutation is a point mutation that only affects one amino acid in a protein sequence.
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