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discuss the relationship among blood cholesterol, saturated fat intake and cardiovascular disease.

discuss the relationship among blood cholesterol, saturated fat intake and cardiovascular disease.
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Cardiovascular disease (CVD) is the number-one cause of death and disability worldwide. Dietary improvements have the potential to significantly reduce the prevalence of CVD. It is well established that saturated fatty acids (SFA) increase low-density lipoprotein (LDL) cholesterol, a strong risk factor for CVD. Dietary fat might contribute to CVD via inflammatory and oxidative stress mechanisms. Polyunsaturated fatty acid (PUFA) can decrease the production of inflammatory and reactive oxygen species, saturated fatty acid (SFA) and trans fatty acids (TFA) can increase pro-inflammatory and oxidative stress, excessive oxidative stress and inflammation contributes to the development of CVD.

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