Question

1. Two people who are “carriers” of (heterozygous) for Tay Sachs disease marry and plan a family. What is the probability that a child from this union will suffer from Tay Sachs disease. (Recall that this is an autosomal recessive disorder, that is, homozygous recessives have the disease.)

   a. Zero b. 0.25 c. 0.5 d. 0.75 e. 1.0

6. At Hardy-Weinberg equilibrium, heterozygotes are the most common genotype in the population when-

a. b. c. d .

p> 0.67
q>0.67 and p<0.33 0.33<p>0.67
p =/ q

7. Inbreeding in a population

   1. Leads to a reduction in heterozygotes

   2. Results from panmictic mating

   3. Changes allele frequencies

   4. Only occurs during self-fertilization

8. Which of the following is NOT an important assumption of the Hardy-Weinberg principle?

   1. Infinitely large population

   2. No gene flow between other populations

   3. Mating is random

   4. Natural selection occurs

   5. No net mutation from one allelic state to another

9. In what sense is Hardy-Weinberg a null hypothesis, similar to a control group in an experiment?

   1. It defines what genotypic frequencies should be if nonrandom mating is occurring.

   2. Expected genotypic frequencies can be calculated from observed allele frequencies and compared with the observed genotypic frequencies.

   3. It defines what genotypic should be if natural selection, genetic drift, gene flow, or mutation is occurring and if mating is random.

   4. It defines what genotypic frequencies should be if evolutionary mechanisms are not occurring.

10. The genotypic frequencies in a two-allele gene system at Hardy-Weinberg equilibrium may be expressed as

    1. p+q=1

    2. p^2 +2pq +q^2=1

    3. p^2 + 2pq

    4. p=1-q

    5. q^2

11. The phenotypic frequencies of a dominant trait in a two-allele gene system at Hardy- Weinberg equilibrium where one allele (p) is dominant over the other (q) may be expressed as

    1. p+q=1

    2. p^2 +2pq +q^2=1

    3. p^2 + 2pq

    4. p=1-q

    5. q^2

12. Genetic drift is aptly named because-

    1. It results in allele frequencies to drift up or down randomly

    2. It is the ultimate source of genetic variability

    3. It is especially important in large mobile populations

    4. It drifts genes towards the optimal phenotype

13. In terms of genetic drift, what does “fixation” mean?

    1. Gene changes from having two or more alleles to just one.

    2. Gene therapies correct the pathological mutation.

    3. One allele is dominant to all others.

    4. An allele is adaptive.

14. Fixation is most likely to occur in a population that is

    1. Infinitely large.

    2. Very large (n>10,000)

    3. Very small (e.g., n<20)

15. A small population breaks away from a very large one and disperses to a new habitat. It

    is an imperfect sample of (i.e., different from) the genome of the mother population.

    1. Genetic Drift.

    2. Fixation.

    3. Founder Effects.

    4. Flounder Defects.

Answer 1

QUESTION 5 Aa x Aa A = Unaffected a = Tay Sachs disease 34 Unaffected 74 = 0.25 Tay Sachs disease 1 A AA Аа la Aa aa Aa аа The probability of having an affected child is 0.25 Note: According to Chegg's guidelines, you have to send just one question. Please, send each question separate so all experts can answer each of your questions. Thank you!.