Question

D 4. Which of the following is TRUE regarding the resting state of a neuron? There is more K+ outside of the neuron than there is inside of the neuron. During the resting state, all of the Na+ and K+ leaky channels are nonfunctional The H+-ATPase pump is responsible for establishing the resting electrochemical gradient in the neuron. The outside of the neural cell has a positive charge while the inside of the neural cell has a negative charge.

Answer 1

Ans) the outside of the neural cell has a positive charge while inside of the neural cell has a negative charge. Option d is true.

The resting membrane potential of a cell is - 70mV

Which means that it is more negative inside and is 70mV less charge inside than outside .

It is negative due to more pottasium ions inside cell and more sodium ions outside cell as the cell is impermeable to sodium. The cell pumps 3 Na+ ions outside the cell for 2 K+ ions inside the cell in resting state.

Option a is wrong because in resting state there is more pottasium inside the cell and Ns outside the cell. As the permeability of sodium decreases.

Option B is wrong because the leaky channels are functional during resting state.

The resting neuron pumps sodium out of the cell and pottasium inside the cell. So the leak channels allow movement of these ions across the cell against their concentration gradient. And this action is continuous and establishes a resting membrane potential.

Option c is wrong because the electrochemical gradient is caused by the charge difference across membrane and also by the difference in concentration gradient across the cells.

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