Which enzymes require thiamine as a co-factor A. Isocitrate dehydrogenase and citrate synthase B. Malate dehydrogenase...
Which enzymes require thiamine as a co-factor
A. Isocitrate dehydrogenase and citrate synthase
B. Malate dehydrogenase and alpha-ketoglutarate dehydrogenase
C. Pyruvate dehydrogenase and isocitrate dehydrogenase
D. Pyruvate dehydrogenase and succinyl-CoA synthetase
E. Succinate dehydrogenase and pyruvate dehydrogenase
Homework Answers
Thiamine or TPP (Thiamine pyrophosphate) acts as a cofactor for many biological enzymes. It plays import roles in glucose, lipid, and amino acid metabolism. The following table shows the enzymes and their cofactors:
| Enzyme | Co-factor |
| Isocitrate dehydrogenase | NADP+ |
| Citrate synthase | Doesn't require a metal ion cofactor |
| Malate dehydrogenase | NAD+/NADP+ |
| Alpha-ketoglutarate dehydrogenase | Thiamine (TPP) |
| Pyruvate dehydrogenase | Thiamine (TPP) |
| Isocitrate dehydrogenase | NADP+ |
| Pyruvate dehydrogenase | Thiamine (TPP) |
| Succinyl-CoA synthetase | vitamin B12 |
| Succinate dehydrogenase | FAD |
| Pyruvate dehydrogenase | Thiamine (TPP) |
The enzymes Pyruvate dehydrogenase, Alpha-ketoglutarate dehydrogenase require TPP as a cofactor.
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Which enzymes require thiamine as a co-factor
A. Isocitrate dehydrogenase and citrate synthase
B. Malate dehydrogenase...
the citric acid cycle has 8 enzymes: citrate synthase, aconitase, isocitrase dehydrogenase,.... 1 Jom L C...
the citric acid cycle has 8 enzymes: citrate synthase,
aconitase, isocitrase dehydrogenase,....
1 Jom L C Tegulation TCA cycle (Ch. 16) 1. The citric acid cycle has eight enzymes: citrate synthase, aconitase, isocitrate dehydrogenase, a-ketoglutarate dehydrogenase, succinyl-CoA synthetase, succinate dehydrogenase, fumarase, and malate dehydrogenase. (a) Write a balanced equation for the reaction catalyzed by each enzyme. (b) Name the cofactor(s) required by each enzyme reaction. (c) For each enzyme determine which of the following describes the type of reaction(s) catalyzed:...
Which of the following citric acid cycle enzymes lead to the formation of NADH and are...
Which of the following citric acid cycle enzymes lead to the formation of NADH and are regulatory enzymes? Isocitrate dehydrogenase Succinyl-CoA synthetase Succinate dehydrogenase Malate dehydrogenase • Citrate synthase
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column...
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hint(s) Reset Help isocitrate dehydrogenase aconitase citrate synthase fumarate hydratase succinate dehydrogenase succinyl-CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase In step 1, oxaloacetate condenses with acetyl-CoA to form citrate, which is catalyzed by...
not sure about reaction 3 and 4 acetyl-CoA COA The reactions of the citric acid cycle...
not sure about reaction 3 and 4
acetyl-CoA COA The reactions of the citric acid cycle are shown in the figure Reactions 1, 3, and 4 are regulation points in the citric acid cycle. 1 citrate oxaloacetate 1 synthase citrate NADH + NAD malate dehydrogenase aconitase 2 malate Which of the molecules inhibits reaction 1? Isocitrate HO 17 fumarase NAD socitrate 3 dehydrogenase S D NADP ADP ОАТР O citrate synthase fumarate FADHI succinate co-ketoglutarate dehydrogenase ci-ketoglutarate NAD dehydrogenase +...
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d....
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d. lactic acidemia e. pellagra syrup urine disease b, phenylketonuria c. galactosemia 10. Chemical modification by phosphorylation of pyruvate dehydros a. deactivates the enzyme b. activates the enzyme lation of pyruvate dehydrogenase complex : 17. Pyruvate carboxylase is positively ated through the allosteric mechanism by : a. ATP b. NADH c. Acetyl-SCOA d. TPP e. Biotin 18. Which of the listed coenzymes does not particip...
Please help 5. The following questions relate to the citrate cycle. 6 a. Match the letters...
Please help
5. The following questions relate to the citrate cycle. 6 a. Match the letters to the citrate cycle intermediates b. Match thenumbers to the citrate cycle enzymes Aconitase Citrate synthase a-Ketoglutarate dehydrogenase Malate dehydrogenase Succinate dehydrogenase Succinyl-CoA synthetase ....Fumarase Isocitrate dehydrogenase. c. Match the numbers to the reaction type for each enzyme. condensation isomerization oxidation hydration hydrolysis, substrate level phosphorylation oxidative decarboxylation
11. Which enzyme is NOT part of the TCA cycle? A. Citrate synthase B. Succinate dehydrogenase...
11. Which enzyme is NOT part of the TCA cycle? A. Citrate synthase B. Succinate dehydrogenase C. alpha-ketoglutarate dehydrogenase D. Aconitase E. Pyruvate dehydrogenase
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ?...
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? :a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. α-ketoglutarate dehydrogenase complex\}c. citrate synthase10. Name the enzyme catalyzing the following reaction:a. PEP carboxykinaseb. pyruvate kinasec. malic enzymed. pyruvate carboxylase11. Name the enzyme that catalyzes the reaction:glyoxylate +CH3CO-SCoA → malate + HSCoAa. malate synthaseb. succinate thiokinasec. aconitased. isocitrate
12. Which enzyme catalyzes the reaction shown? Oo 9% a. succinyl-CoA synthetase b. succinate dehydrogenase c....
12. Which enzyme catalyzes the reaction shown? Oo 9% a. succinyl-CoA synthetase b. succinate dehydrogenase c. pyruvate dehydrogenase d、a-ketoglutarate dehydrogenase 13. Which of the reactions of the citric acid cycle requires FAD as a coenzyme? a. the conversion of isocitrate to a-ketoglutarate b. the conversion of citrate to isocitrate c. the conversion of succinate to fumarate d. the conversion of malate to oxaloacetate 14. Another name for Complex I in the electron transport chain is a. cytochrome c oxidase. b....
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled...
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled in the diagram, reactions 1, 3, and 4 are regulation points in the citric acid cycle. oxaloacetate citrate synthase citrate NADH +Hi 7 malate dehydrogenase NAD malate aconitase 2 Which molecule inhibits reaction 1? isocitrate 7 fumarase NAD isocitrate dehydrogenase 3 NADH + H+ O citrate O NAD acetyl-CoA + CO2 fumarate C-ketoglutarate FADH succinate O dehydrogenase FAD O-ketoglutarate a dehydrogenase NAD + COA...
the citric acid cycle has 8 enzymes: citrate synthase,
aconitase, isocitrase dehydrogenase,....
1 Jom L C Tegulation TCA cycle (Ch. 16) 1. The citric acid cycle has eight enzymes: citrate synthase, aconitase, isocitrate dehydrogenase, a-ketoglutarate dehydrogenase, succinyl-CoA synthetase, succinate dehydrogenase, fumarase, and malate dehydrogenase. (a) Write a balanced equation for the reaction catalyzed by each enzyme. (b) Name the cofactor(s) required by each enzyme reaction. (c) For each enzyme determine which of the following describes the type of reaction(s) catalyzed:...
Which of the following citric acid cycle enzymes lead to the formation of NADH and are regulatory enzymes? Isocitrate dehydrogenase Succinyl-CoA synthetase Succinate dehydrogenase Malate dehydrogenase • Citrate synthase
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hint(s) Reset Help isocitrate dehydrogenase aconitase citrate synthase fumarate hydratase succinate dehydrogenase succinyl-CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase In step 1, oxaloacetate condenses with acetyl-CoA to form citrate, which is catalyzed by...
not sure about reaction 3 and 4
acetyl-CoA COA The reactions of the citric acid cycle are shown in the figure Reactions 1, 3, and 4 are regulation points in the citric acid cycle. 1 citrate oxaloacetate 1 synthase citrate NADH + NAD malate dehydrogenase aconitase 2 malate Which of the molecules inhibits reaction 1? Isocitrate HO 17 fumarase NAD socitrate 3 dehydrogenase S D NADP ADP ОАТР O citrate synthase fumarate FADHI succinate co-ketoglutarate dehydrogenase ci-ketoglutarate NAD dehydrogenase +...
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d. lactic acidemia e. pellagra syrup urine disease b, phenylketonuria c. galactosemia 10. Chemical modification by phosphorylation of pyruvate dehydros a. deactivates the enzyme b. activates the enzyme lation of pyruvate dehydrogenase complex : 17. Pyruvate carboxylase is positively ated through the allosteric mechanism by : a. ATP b. NADH c. Acetyl-SCOA d. TPP e. Biotin 18. Which of the listed coenzymes does not particip...
Please help
5. The following questions relate to the citrate cycle. 6 a. Match the letters to the citrate cycle intermediates b. Match thenumbers to the citrate cycle enzymes Aconitase Citrate synthase a-Ketoglutarate dehydrogenase Malate dehydrogenase Succinate dehydrogenase Succinyl-CoA synthetase ....Fumarase Isocitrate dehydrogenase. c. Match the numbers to the reaction type for each enzyme. condensation isomerization oxidation hydration hydrolysis, substrate level phosphorylation oxidative decarboxylation
9. Which of the listed enzymes of the TCA cycle is regulated by phosphorylation/dephosphorylation cycle ? :a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. α-ketoglutarate dehydrogenase complex\}c. citrate synthase10. Name the enzyme catalyzing the following reaction:a. PEP carboxykinaseb. pyruvate kinasec. malic enzymed. pyruvate carboxylase11. Name the enzyme that catalyzes the reaction:glyoxylate +CH3CO-SCoA → malate + HSCoAa. malate synthaseb. succinate thiokinasec. aconitased. isocitrate
12. Which enzyme catalyzes the reaction shown? Oo 9% a. succinyl-CoA synthetase b. succinate dehydrogenase c. pyruvate dehydrogenase d、a-ketoglutarate dehydrogenase 13. Which of the reactions of the citric acid cycle requires FAD as a coenzyme? a. the conversion of isocitrate to a-ketoglutarate b. the conversion of citrate to isocitrate c. the conversion of succinate to fumarate d. the conversion of malate to oxaloacetate 14. Another name for Complex I in the electron transport chain is a. cytochrome c oxidase. b....
acetyl-CoA COA The reactions of the citric acid cycle are shown in the image. As labeled in the diagram, reactions 1, 3, and 4 are regulation points in the citric acid cycle. oxaloacetate citrate synthase citrate NADH +Hi 7 malate dehydrogenase NAD malate aconitase 2 Which molecule inhibits reaction 1? isocitrate 7 fumarase NAD isocitrate dehydrogenase 3 NADH + H+ O citrate O NAD acetyl-CoA + CO2 fumarate C-ketoglutarate FADH succinate O dehydrogenase FAD O-ketoglutarate a dehydrogenase NAD + COA...
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