Question

Search Input Cross-Reacting Species 2 nmol Custom Input Human Design ID CD.RI.219133.13.1 $95.00 USD ADD TO CART Hide product details - 315 630 Cross-Reacting Tran... NM_015017 (USP33), NM_006121 (KRT1), NM_015131 (WDR43), NM_201626 (USP33). NM 201624 (USP33), NM_173631 (ZNF547), NM_007110 (TEP1) Sequence Positions 173-198 Sequence Details Sense and antisense sequences Sequence Strand 5'rArArCrArUrGrGrCrArArGrGrArArGrArCrCrUrUrArArATT 3 5'rArArUrUrUrArArGrGrUrCrUrUrCrCrUrUrGrCrCrArUrGrUrUrGA 3
what is the passenger strand

Answer 1

The passenger strand are found in the siRNA. The RNAi pathway is found in many eukaryotes, including animals, and is initiated by the enzyme Dicer, which cleaves long double-stranded RNA (dsRNA) molecules into short double-stranded fragments.

Each siRNA is unwound into two single-stranded RNAs (ssRNAs), the passenger strand and the guide strand. The passenger strand is degraded and the guide strand is incorporated into the RNA-induced silencing complex.