Histones are highly variable proteins across organisms. (T/F)
False
Histone proteins are highly conserved molecules across eukaryotes. These proteins are associated with DNA and help in the extensive Packaging of DNA inside the nucleus.
There are five types of histone proteins, H1, H2A, H2B, H3 and H4.
Two molecules each of H2A and H2B histone proteins form a tetramer.
Two molecules each of H3 and H4 histone proteins form a tetramer.
Both these tetramers associate with each other to form histone octamer which is the core histone protein molecule. DNA wraps 147 bases around this core histone protein. This is also called as nucleosome.
Two nucleosomes are connected to each other by linker histone protein which is the H1 histone.
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1.I said in class that histones are among the most highly-conserved proteins known, suggesting that almost any change in their sequences would be Very, Very Bad. In terms of mitosis and meiosis, why is maintaining histone function so important to the cell or organism?
Eukaryotic organisms differ from prokaryotic organisms because only eukaryotes have a. polymerases b. histones c. circular chromosomes d. DNA
All of the following are characteristics of animals except exclusively sexual reproduction eukaryotic cells multicellular organisms heterotrophic nutrition O gastrulation All of the following statements concerning homeotic genes is correct except They are responsible for determining the general body plan. They act as master control genes. They code for DNA-binding proteins. They are highly variable across species the animal kingdom.
What is the common between histone proteins and spermiding? 1.)histones and spermidine are present only in bacteria. 2.)histones are spermidine are negatively charged 3.) histones are spermiding help DNA attain a random coil conformation 4.) they both play a role in DNA packaging Which of the following factors makes hydrolysis of acetyl coA a favorable process? 1.)separation of like charges 2.)increased delocalization of the pi-cloud 3.)enol-keto tautomerication 4.) change of non-aromatic structure to aromatic structure The amino acid responsible for...
True/False (6 pts) *if false, correct the statement 1. (True/False) The histone octamer forms a protein core around which the double stranded DNA is wound. 2. (True/False) Histones are highly variable proteins across organisms. 3. (True/False) The interface between DNA and histone has multiple contacts. 4. (True/False) CTCF is a cis-regulatory element that acts as a silencer. 5. (True/False) The modification cytosine to 5-methyl cytosine is associated with gene inactivation and reduced gene expression. 6. (True/False) HATs and HDACs are...
See Hint Several organisms have a homologous protein inherited from a common ancestor) that is highly similar at the amino acid level. You are comparing the genes that code for these proteins in the different organisms when you note that one of the codon nucleotide positions shows more nucleotide variation than the other nucleotide positions. In which codon nucleotide position do you expect to see the most variability among species? Choose one: A fourth nucleotide position B. third nucleotide position...
If the amino acid sequences in homologous proteins of two organisms are similar, what can you conclude about the DNA of the two organisms?
Notch / Jagged (Delta) Pathway Highly conserved cell signaling system present in most multicellular organisms; Controls multiple cell differentiation processes during embryonic and adult life; Notch signaling is disregulated in many cancers and other diseases including T-ALL (T-cell acute lymphoblastic leukemia), CADASIL (Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy), MS (Multiple Sclerosis) and myriad other disease states. Highly conserved cell signaling system present in only animal cells
Question 5 QUESTION 2 What is common between histone proteins and spermidine? Histones and Spermidine are negatively charged. Histones and spermidine help DNA attain a random coil conformation They both play a role in DNA packaging. Histone and spermidine are present only in bacteria. QUESTION 3 Which of the following is NOT is product of Kreb's cycle NAD+ ATP FADH2 CO2 QUESTION 4 The amino acid responsible for introducing kinks in DNA helical structure by intercalation is Phenylalanine Ethidium Bromide...
Proteins are one of the three macronutrients found in the diet and important structural molecule organisms. Proteins help provide structure to cells and are the major component of enzymes that pa biological reactions. While all macronutrients share similarities, proteins are different than both care lipids in important ways. The following statements are all true regarding amino acids and proteins. Select which statements al proteins alone and which statements are true of all proteins, carbohydrates, and fats. The human body is...