Question

microbiolgy if you can help

BI A X A D X A A Paragraph A Styles Sensitivity 1. Through what mechanisms do viruses invade eukaryotic cells? How do these approaches compare for "naked" vs. "enveloped" viruses? 2.What different strategies do enveloped viruses use to access the cytosol? 3.What is a viral "replication factory" and where would these be found? 4. What happens to other cellular functions when a replication factory is formed

Answer 1

Viruses enter the cell by three different mechanisms, membrane fusion, endocytosis or via genetic conjugation. Before a virus enters the cell it must attach to the surface of the host cell. Attachment of viruses to the host membrane occurs through the interaction of viral coat proteins (capsid) or envelope with the host membrane protein called receptors. once a virus attaches to the surface it may, (1) fuse with host phospholipid membrane and puncture it to enter the cell, (2) get endocytosed as a food particle or (3) or release it's DNA/RNA directly after attachment.

The enveloped viruses virus may enter the cell by the fusion or endocytosis mechanism while the naked viruses directly inject their genetic content after attachment.

Direct injection of genetic material

Uncoating Endocytosis & Oncoating of enveloped viruses

au Enveloped Viral-membrane fusion