Contrast the terms agonist and antagonist using acetylcholine as an example
What is the difference between an agonist, partial agonist, antagonist and inverse agonist? Use an example of a psychiatric drug from each category explaining the mechanism of action.
(c) Define the terms agonist and antagonist and discuss how the breast cancer drug, tamoxifen, acts an antagonist for the human estrogen receptor while estradiol acts a natural agonist for this same receptor. estradiol tamoxifen
What is the agonist to antagonist spectrum of action of psychopharmacologic agents?
The acetylcholinesterase enzyme functions to break down acetylcholine in a synapse. How would an antagonist of acetycholinestrrase affect the half life of acetylcholine in a synapse?
Assuming that you had an agonist and an antagonist for every autonomic transmitter receptor, how could you determine which receptor types exist in any autonomically controlled effector? Using the method you defined in Question 1 and your knowledge of the Autonomic control of the function of the internal organs, predict the effects (increase, decrease, or no change) of the following autonomic agonists on heart rate (HR). AGONIST HR CHANGE alpha-adrenergic beta-adrenergic muscarinic nicotinic Using autonomic pharmacological agents, how could you...
Define agonist (prime mover) and antagonist muscles. Describe and explain the differences that you observe in the EMGs recorded from the two muscles during different actions
Motion Analysis: leg curl Lifting Phase (AB) In that role, contraction type? Role A (agonist/antagonist) Semitendinosus Rectus Femoris B Popliteus Sartorius Lowering Phase (BA) Semimembranosus Sracilis Vastus intermedius Motion Analysis: leg curl Lifting Phase (AB) In that role, contraction type? Role A (agonist/antagonist) Semitendinosus Rectus Femoris B Popliteus Sartorius Lowering Phase (BA) Semimembranosus Sracilis Vastus intermedius
1. Any compound, either natural or synthetic, that stimulates specific receptors is called an (agonist/antagonist). Which is correct?
1. State the responses that a muscarinic agonist would be expected to cause through direct activation of muscarinic cholinergic receptors (consider bethanechol). The student should focus on the main “targets” of parasympathetic nervous system activity: eyes, respiratory system, heart and blood vessels, gastrointestinal (GI) and urinary tracts, and the secretory activity of exocrine glands (e.g., lacrimal, mucous, and so on). 2. List cholinergic responses not normally caused when the usual therapeutic doses of a muscarinic agonist are administered and explain...
Selective Estrogen Receptor modulators (SERMS) have two applications. Describe the applications and types of compounds (Agonist/antagonist) used for each application. Application 1: Application 2: How is this situation similar to the clinical situation for beta-receptors?