Question

Fill in the blank (7pts) 5. Histone is a linker histone that can affect nucleosome packing. 6. The p in the CpG motif refers to 7. The yeast Gall gene is regulated by trans-acting activators and repressors. The repressor protein is called 8. The activator protein of the Gall locus is called 9. The repressor protein for the Gall locus (does not / does) contain a DNA binding domain. 10. Deamination of cytosine results in 11. Deamination of 5-methyl cytosine results in

Answer 1

Question 5.

Histones H1 is a linker histone that can affect nucleosome packing.

Histone are positively charged protein, help in DNA packing. Histone protein is of two types- Core histone proteins and linker histone proteins.

Core histone forms an octamer and DNA wraps on it, forming a nucleosome. Example- H2A, H2B, H3, and H4.

Linker histone help in linking two nucleosome unit. Example- H1.

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