Question

Question 4, regarding gene linkage and recombination mapping. Stuck behind the concepts on how to answer the highlighted question, regarding gene linkage and recombination mapping.

Suppose these are two of your homologous chromosomes as they exist in Your somatic cells. Several heterozygous loci are indicated by letters, and the distances between them in map units is indicated to the right. For problems 3 and 4, round to nearest whole number. 2. Crossover is MOST likely to occur between which two genes? a. T&A b. B & E C. R&B d. R & E e. T&R 15 m.u. 3. Which of the following genotypes would be MOST rare in your gametes? a. tr. b. AB c. Ra d. BE <-------->- < : 25 m.u. 4. Which % of your gametes are expected to have the genotype te? a. 39 b. 61 C. 50 d. 25 e. 31 9 m.u. -----> b 5. Which is the key aspect of both Sanger and cyclic reversible termination sequencing that allows one to determine the sequence of a DNA sequence? a. gel electrophoresis C. chain termination (not necessarily permanant) b. heat-stable DNA polymerase d. unique fluorescent label for each base <------> 12 m.u. Doboy Asterminal haliy CRE

Answer 1

4) answer will be d option i.e 31 mu or morgen unit

Total distance of t-e gene is 15+25+9+12= 61mu

Now after crossing between t-e two type gametes will form one will be T-E while another one is t-e so each one has 61/2 = 30.5 mu

So recombination frequency for T-E is 30.5 mu and T- e is also 30.5 mu

Here in question its asked for T-E which is 30.5 ~31mu so answe will be d option.

Hope its clear..thanks