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The answer is e. Why would it be the delta and beta genes? I was thinking it would be the pseudogene.

24. Consider the diagram of the B-globin locus below. Which of the following is most likely to lead to persistent expression

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persistant expression of embryonic globin in adult is iften characterized by some disorders such as beta thalassemia and sickle cell anemia. In this the reduced or absence of alpha and beta genes results in icreased expression of HbF and presence of hypochromic and microlytic blood cells. It results in hereditary persistance of fetal hemoglbin (HBFF). This is due to mutations in the beta gene clusters and leads to increased production of HbF leading to inability to switch from HbF to HbA mode in adults. Both genes alpha and beta are located on chromosome 16 and chromosome 11 respectively. It encodes HBA1 and HBA2 respectively.

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