QUESTION 4
Small intestine is the major site of digestion and absorption of carbohydates, proteins and fats. Chyme (food in intestine) are mixed with a) intestainal juice b) pancreatic juice and c) bile.
Enzymes of intestinal juice (succus entericus)
1.Enzyme for carbohydarte digestion
( a) Invertase
(b) Maltase
(c) Lactase
(d) alpha limiting dextrinase
2. Proteolytic enzyme -protein digestion
(a) Erepsin ( mixture of several peptidases)
(b) Nuclease (nucleotidase, nucleosidade)
3. Intestinal lipase -fat digestion
4. Enterokinase - activates trypsin
5. Cholestrol esterase - convert cholestro esters to free cholestrol
6. Lecithinase-convert lecithin into simpler phospholipid
7. Alkaline phosphatase-organic phosphate into free phosphate
Types of Digestion
carbohyderate digestion : dissaccharids are converted into monasaccharides in the intestine
( end product each reaction along with the enzymes involved)
invertase
I) sucrose ------------------------> glucose and fructose
maltase
II) maltose ---------------------> 2 molucules of glucose
lactase
III) lactose ----------------------> glucose and galactose
alpha limiting dexterinse
IV) alpha limiting dexterins -------------------------------------> glucose
Fat Digestion
Lipase hydrolyses fat to monoglycerides.Majority of fat digestion occurs in the small intestine.
lipase lipase lipase
Thus, enzyme lipase, bile salts, panceratic juice are all involved in the fat digestion.
Protein
All proteolytice enzynmes are produced in inactive frorms and they are later activated in the stomach and small intestine duing the time of digestion . This is kind of bodys precaution to prevent the lysis of the intestinal walls by the proteolytic enzymes. Enzyme entrokinase( present in interstinal juice) activates trypsinogen which is later activated into trypsin.
trypsin and chymotrypisin
peptones --------------------------------------> small polypeptides
carboxy peptidases
polypetides ------------------------------------> peptides
erepsin
peptides ------------------------------------> free amino acids
nuclease nucleotides and nucleosides
nucleic acid --------------------------> nucleotides and nucleosides -----------------------------------> purine and pyrimidine
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