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10. DNA is more ____________ than RNA due to the absence of ______ group in the...

10. DNA is more ____________ than RNA due to the absence of ______ group in the ribose.

A. unstable, 3'-OH

B. stable, 3'-OH

C. unstable, 2'-OH

D. stable, 2'-OH

E. none of the above

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Answer #1

the right option is D. stable , 2'-OH

explation: DNA is more resistance to hydrolysis due to the absence of the 2'-OH group. in the presence of nucleophilic species, a 2'-OH would hydrolyze the phosphodiester linkage and cause a break in the nucleic acid backbone.

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