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Many extracellular proteins are internalized by receptor-mediated endocytosis. What are the molecular signals that trigger uptake...

Many extracellular proteins are internalized by receptor-mediated endocytosis. What are the molecular signals that trigger uptake of a protein by receptor mediated endocytosis?

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Answer:- Binding of ligand molecule to specific receptor induce endocytosis pathway. in following example ldl molecule induce endocytosis pathway is depicted. when ldl molecule binds to specific receptor it activates series of reaction which ultimately leads to endocytosis. like ldl there are other molecule which activate endocytosis pathway for specific ligand- receptor for example high egf, GPCR ligand etc.

L LDL receptors plasma membrane CYTOSOL TIEND ENDOCYTOSIS coated pit UNCOATING recycling endosome RETURN OF LDL RECEPTORS TO

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