Homework Answers
C. The same as the substrate analogue
Transition state analog - Chemical compounds with a chemical structure that resembles the transition state of a substrate molecule in an enzyme-catalyzed chemical reaction. Transition state analogs usually do not undergo a chemical reaction and can act as enzyme inhibitors by blocking their active site.
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Transition state analogues: Unanswered Kd of a transition state analogue would be expected to be lower...
Descriptions of enzyme mechanisms often contain the terms reaction intermediate, transition state, and transition state analogue....
Descriptions of enzyme mechanisms often contain the terms
reaction intermediate, transition state, and transition state
analogue. The terms intermediate and transition state both describe
chemical species along the reaction pathway, but there are
important distinctions between the two. Transition state analogues
are often used in enzyme mechanism studies. Match the phrases to
the term that they describe. Scroll down to see all the items.
Descriptions of enzyme mechanisms often contain the terms reaction intermediate, transition state, and transition state analogue....
( --/ Question 1 What is the incorrect statement about catalysis? The enzyme-substrate complex has lower...
( --/ Question 1 What is the incorrect statement about catalysis? The enzyme-substrate complex has lower free energy than the free substrate The stronger the enzyme-substrate interaction, the higher the Km value. At very high substrate concentrations, the reaction rate is independent of the substrate concentration. The enzyme-substrate complex is not the transition-state molecule. The higher the turnover number of a catalyst, the lower the catalyst concentration needed to reach a certain maximum reaction rate.
A rate enhancement of 106 requires that the enzyme bind its transition state complex with higher...
A rate enhancement of 106 requires that the enzyme bind its transition state complex with higher affinity than its substrate. Using the Arrhenius equation, shown before this part, find ΔΔG‡cat for a rate enhancement of 10^6 at 298 K. Express ΔΔG‡cat in kJ/mol to three significant figures.
10. A good transition-state analog: A) binds covalently to the enzyme. B) binds to the enzyme...
10. A good transition-state analog: A) binds covalently to the enzyme. B) binds to the enzyme more tightly than the substrate. C) binds very weakly to the enzyme. D) is too unstable to isolate. E) must be almost identical to the substrate. 11. Which factor bas NOT been shown to play a role in determining the specificity of protein kinases? A) disulfide bonds near the phosphorylation site B) primary sequence at phosphorylation site C) protein quaternary structure D) protein tertiary...
For the hydrogen atom, the transition from the 2p state to the 1s state is accompanied by the emi...
For the hydrogen atom, the transition from the 2p state to the 1s state is accompanied by the emission of a photon with an energy of 16.2x10-19 J. For a Ni atom, the same transition (2p to 1s) is accompanied by the emission of x-rays of wavelength 1.66 A. What is the energy difference between these states in nickel? The energy difference between these states in nickel is the corresponding energy difference for hydrogen The energy difference between these states...
For the hydrogen atom, the transition from the 2p state to the 1s state is accompanied by the emi...
options for 2 and 3 are <,>, or =
For the hydrogen atom, the transition from the 2p state to the 1s state is accompanied by the emission of a photon with an energy of 16.2x1019 J. For a Ga atom, the same transition (2p to 1s) is accompanied by the emission of x-rays of wavelength 1.34 A. What is the energy difference between these states in gallium? The energy difference between these states in gallium is v the corresponding...
For the hydrogen atom, the transition from the 2p state to the is state is accompanied...
For the hydrogen atom, the transition from the 2p state to the is state is accompanied by the emission of a photon with an energy of 16.2x10-19 J. For a Cl atom, the same transition (2p to 1s) is accompanied by the emission of x-rays of wavelength 4.73 A. What is the energy difference between these states in chlorine? The energy difference between these states in chlorine is the corresponding energy difference for hydrogen. The energy difference between these states...
biochemistry if you could please help me answer the following questions! 741) (5 pts) Transition state theory relate...
biochemistry
if you could please help me answer the following questions!
741) (5 pts) Transition state theory relates the rate constant to the free energy of activation, AG. How can enzymes reduce the activation energy barrier? a) decrease the free energy of the product b) high affinity binding to the transition state c) increase the free energy of the substrate d) increase entropy upon release of product e) bind to the substrate with high affinity 2) (5 pts) Which is...
Question 4 Enzymes... ... lower the transition state energy of the uncatalyzed reaction. ... create energy...
Question 4 Enzymes... ... lower the transition state energy of the uncatalyzed reaction. ... create energy to make reactions favorable. 1 ...slow reaction rates to maintain a steady state, thus avoiding sudden changes. ...bind most strongly to reactants in order to allow reaction. ... accelerate the attainment of equilibrium. Question 5
Match each definition with the appropriate name. Choices: absorption, emission, excited state, ionization, ground state, transition....
Match each definition with the appropriate name. Choices: absorption, emission, excited state, ionization, ground state, transition. • any energy state of an atom except the ground state. • the lowest energy state of an atom. • a photon of light causes an electron to jump to a higher energy state. • a photon strikes an atomic electron and removes it from the atom. • an electron falls to a lower energy state and a photon is created. • a jump...
Descriptions of enzyme mechanisms often contain the terms
reaction intermediate, transition state, and transition state
analogue. The terms intermediate and transition state both describe
chemical species along the reaction pathway, but there are
important distinctions between the two. Transition state analogues
are often used in enzyme mechanism studies. Match the phrases to
the term that they describe. Scroll down to see all the items.
Descriptions of enzyme mechanisms often contain the terms reaction intermediate, transition state, and transition state analogue....
( --/ Question 1 What is the incorrect statement about catalysis? The enzyme-substrate complex has lower free energy than the free substrate The stronger the enzyme-substrate interaction, the higher the Km value. At very high substrate concentrations, the reaction rate is independent of the substrate concentration. The enzyme-substrate complex is not the transition-state molecule. The higher the turnover number of a catalyst, the lower the catalyst concentration needed to reach a certain maximum reaction rate.
10. A good transition-state analog: A) binds covalently to the enzyme. B) binds to the enzyme more tightly than the substrate. C) binds very weakly to the enzyme. D) is too unstable to isolate. E) must be almost identical to the substrate. 11. Which factor bas NOT been shown to play a role in determining the specificity of protein kinases? A) disulfide bonds near the phosphorylation site B) primary sequence at phosphorylation site C) protein quaternary structure D) protein tertiary...
For the hydrogen atom, the transition from the 2p state to the 1s state is accompanied by the emission of a photon with an energy of 16.2x10-19 J. For a Ni atom, the same transition (2p to 1s) is accompanied by the emission of x-rays of wavelength 1.66 A. What is the energy difference between these states in nickel? The energy difference between these states in nickel is the corresponding energy difference for hydrogen The energy difference between these states...
options for 2 and 3 are <,>, or =
For the hydrogen atom, the transition from the 2p state to the 1s state is accompanied by the emission of a photon with an energy of 16.2x1019 J. For a Ga atom, the same transition (2p to 1s) is accompanied by the emission of x-rays of wavelength 1.34 A. What is the energy difference between these states in gallium? The energy difference between these states in gallium is v the corresponding...
For the hydrogen atom, the transition from the 2p state to the is state is accompanied by the emission of a photon with an energy of 16.2x10-19 J. For a Cl atom, the same transition (2p to 1s) is accompanied by the emission of x-rays of wavelength 4.73 A. What is the energy difference between these states in chlorine? The energy difference between these states in chlorine is the corresponding energy difference for hydrogen. The energy difference between these states...
biochemistry
if you could please help me answer the following questions!
741) (5 pts) Transition state theory relates the rate constant to the free energy of activation, AG. How can enzymes reduce the activation energy barrier? a) decrease the free energy of the product b) high affinity binding to the transition state c) increase the free energy of the substrate d) increase entropy upon release of product e) bind to the substrate with high affinity 2) (5 pts) Which is...
Question 4 Enzymes... ... lower the transition state energy of the uncatalyzed reaction. ... create energy to make reactions favorable. 1 ...slow reaction rates to maintain a steady state, thus avoiding sudden changes. ...bind most strongly to reactants in order to allow reaction. ... accelerate the attainment of equilibrium. Question 5
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