Protein A binds to the IgGs of different species of animals with variable affinity. What does...
Protein A binds to the IgGs of different species of animals with variable affinity. What does this difference tell you about the Protein A epitope?
a. the epitopes of the species are identical
b. Some species lack IgGs and therefore cannot bind to Protein A
c. the epitopes are similar, but with enough difference that it makes the affinity variable.
d. The epitopes are very different in all the species
Provide reasoning with your answer.
d.
Homework Answers
C is correct answer because epitope for protein A are similar as antigen is same but IgG of different species have enough difference in their structures that their binding affinity is variable.
One could bind strongly and other weakly. This is reason that one molecule can be antigen in one species but not in another.
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